Parkinsons Disease Clinical Trials

9 recruiting

Parkinsons Disease Trials at a Glance

20 actively recruiting trials for parkinsons disease are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Toronto, New York, and Farmington Hills. Lead sponsors running parkinsons disease studies include InSightec, BlueRock Therapeutics, and BioVie Inc..

Browse parkinsons disease trials by phase

Treatments under study

About Parkinsons Disease Clinical Trials

Looking for clinical trials for Parkinsons Disease? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Parkinsons Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Parkinsons Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 3

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

Parkinsons Disease (PD)
BlueRock Therapeutics102 enrolled39 locationsNCT06944522
Recruiting
Phase 1

First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)

Parkinsons Disease
Regeneron Pharmaceuticals46 enrolled2 locationsNCT07216066
Recruiting
Phase 1

Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

Parkinsons Disease (PD)
Pravat Mandal12 enrolled1 locationNCT07064005
Recruiting

Neuroimaging of Parkinson's

Parkinsons Disease (PD)
Washington University School of Medicine120 enrolled1 locationNCT07024875
Recruiting

Udall Project 1 Aim 4

Deep Brain StimulationParkinsons Disease
University of Minnesota100 enrolled1 locationNCT05568199
Recruiting
Phase 1

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

Multiple System AtrophyParkinsons Disease
Craig van Horne, MD, PhD7 enrolled1 locationNCT06683365
Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Movement DisordersParkinsons DiseaseNeurology
InSightec60 enrolled5 locationsNCT05539196
Recruiting
Not Applicable

Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers

MindfulnessMovement DisordersCaregivers+4 more
The University of Hong Kong200 enrolled1 locationNCT06821230
Recruiting
Not Applicable

Exergaming for Imrpving Upper Limb Functions in Parkinson's Disease

Parkinsons Disease (PD)
University of Health Sciences Lahore30 enrolled1 locationNCT07475741
Recruiting
Not Applicable

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

Mild Cognitive Impairment (MCI)Parkinsons Disease (PD)Healthy Adult
University of Colorado, Denver80 enrolled1 locationNCT07424365
Recruiting

Research Into the Expression of the csgA-gene and How it Changes in Patients With Parkinson's Disease

Parkinsons Disease (PD)
Vertero Therapeutics200 enrolled1 locationNCT07175922
Recruiting
Not Applicable

Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD

Parkinsons Disease (PD)
Sanford Health64 enrolled1 locationNCT06883266
Recruiting
Not Applicable

MR-guided Focused Ultrasound Plus GCase

Parkinsons Disease
InSightec14 enrolled1 locationNCT05565443
Recruiting

Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease

Oropharyngeal DysphagiaParkinsons Disease (PD)
Heinrich-Heine University, Duesseldorf100 enrolled1 locationNCT07299448
Recruiting
Not Applicable

Revision of Deep Brain Stimulator in Patients With Parkinson's Disease

Pain ManagementRegional AnesthesiaDeep Brain Stimulation+1 more
Ankara Etlik City Hospital50 enrolled1 locationNCT07176494
Recruiting
Phase 2

Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

Prodromal Parkinsons Disease
Michael J. Fox Foundation for Parkinson's Research100 enrolled8 locationsNCT07265596
Recruiting
Phase 3

Edmond J. Safra Accelerating Clinical Trials in Parkinson's Disease: A Multiarm Multi-stage Platform Trial

Parkinsons Disease (PD)
University College, London1,200 enrolled2 locationsNCT07207057
Recruiting
Phase 2

A Study of NE3107 in Early Parkinson's

Parkinsons Disease (PD)
BioVie Inc.60 enrolled4 locationsNCT06757010
Recruiting
Not Applicable

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Alzheimer Disease, Early OnsetParkinsons Disease with DementiaNon Pharmacological Intervention
University Hospital, Montpellier120 enrolled3 locationsNCT06688968
Recruiting

Effects of combined arm and leg high-intensity interval training on motor and non-motor symptoms in people with mild to moderate Parkinson's disease: A randomised controlled feasibility trial

Parkinsons Disease
University of Sydney30 enrolled1 locationACTRN12623001279617