RecruitingNot ApplicableNCT07220876

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial of the Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma


Sponsor

Avisi Technologies Inc.

Enrollment

165 participants

Start Date

Nov 7, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial


Eligibility

Min Age: 45 Years

Inclusion Criteria5

  • Open angle, pseudoexfoliative or pigmentary glaucoma
  • IOP at preoperative visit of ≥ 20mmHg and ≤ 40mmHg
  • Visual field mean deviation score of -3dB or worse
  • Area of healthy, free and mobile conjunctiva in the target quadrant
  • Shaffer angle grade ≥ 2 in the target quadrant

Exclusion Criteria7

  • Angle closure glaucoma
  • Congenital, neovascular or other secondary glaucomas
  • Previous intraocular surgery, with the exception of uncomplicated cataract surgery
  • Previous glaucoma shunt/valve in the target quadrant
  • Clinically significant inflammation or infection in the study eye within 30 days prior to the operative visit
  • History of corneal surgery, corneal opacities or corneal disease
  • Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition

Interventions

DEVICEVisiPlate Glaucoma Implant

Implant (micro-shunt) for glaucoma patients


Locations(12)

Arizona Advanced Eye Research

Glendale, Arizona, United States

Sacramento Eye Consultants

Sacramento, California, United States

ICON Eye Care

Grand Junction, Colorado, United States

Mile High Eye Institute

Sheridan, Colorado, United States

Cleveland Clinic- Cole Eye Institute

Cleveland, Ohio, United States

Scheie Eye Institute

Philadelphia, Pennsylvania, United States

Wills Eye Hospital

Philadelphia, Pennsylvania, United States

Glaucoma Associates of Texas

Dallas, Texas, United States

University of Texas Southwestern

Dallas, Texas, United States

The Eye Centers of Racine & Kenosha

Kenosha, Wisconsin, United States

Lynette Venter

Bloemfontein, South Africa

Pretoria Eye Institute

Pretoria, South Africa

View Full Details on ClinicalTrials.gov

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NCT07220876


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