RecruitingNot ApplicableNCT07239219

The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

To Determine the Efficacy of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.


Sponsor

Ohio State University

Enrollment

300 participants

Start Date

Dec 31, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates. By comparing Irrisept to saline irrigation, the study will provide critical insights into the efficacy of antiseptic bladder irrigation in preventing UTIs while minimizing antibiotic use. If successful, this approach could lead to new clinical guidelines for catheter removal protocols, improving patient outcomes and reducing healthcare costs.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Presenting to the urology clinic for catheter removal
  • Must be 18 years or older.
  • The patient must be able to understand and willing to provide informed consent as described in this study protocol.
  • Must be willing to complete a post-catheter removal survey

Exclusion Criteria7

  • Allergy or adverse reaction to chlorohexidine gluconate
  • Under the age of 18
  • Refuse to provide informed consent
  • On antibiotic therapy for any indication.
  • Women who are pregnant or breastfeeding
  • Signs of skin or systemic infection
  • Patients undergoing catheter exchange

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Interventions

OTHER0.05% Chlorhexidine Gluconate

0.05% CHG is instilled into the bladder prior to trial of void.

OTHERNormal Saline

Bladder is back filled with normal saline.


Locations(1)

The Ohio State University

Columbus, Ohio, United States

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NCT07239219


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