RecruitingNot ApplicableNCT07241182

Antrodia Cinnamomea Extract Effects on Lung Cancer Patients' Quality of Life During Chemotherapy

The Effects of Antrodia Cinnamomea Fruiting Body Extract on Quality of Life and Chemotherapy Side Effects in Patients With Lung Cancer Undergoing Platinum-Based Chemotherapy


Sponsor

Tri-Service General Hospital

Enrollment

40 participants

Start Date

Nov 24, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized trial will test whether Antrodia cinnamomea supplement improves quality of life in lung cancer patients receiving platinum-based chemotherapy. Participants at Tri-Service General Hospital will be randomized to receive either Antrodia cinnamomea capsules or placebo for 3 months, with follow-up to 6 months (24 weeks). Primary outcomes include nausea/vomiting scores, sleep quality, quality of life, and cancer symptoms.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a natural mushroom extract from Antrodia cinnamomea — a medicinal fungus used in traditional Taiwanese medicine — can improve quality of life and reduce side effects for lung cancer patients undergoing platinum-based chemotherapy. **You may be eligible if...** - You have been diagnosed with lung cancer confirmed by imaging and pathology - You are 18 years or older - You are currently receiving or planned to receive platinum-based chemotherapy - You have a life expectancy of at least 6 months **You may NOT be eligible if...** - You have abnormal liver or kidney function in recent lab tests - You have had unexplained high fever or chronic diarrhea recently - You are currently receiving hormone therapy - You have significant heart disease or severe neuropathy - You have an active infection or known allergy to the supplement - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTAntrodia cinnamomea supplement

Intervention Description: Oral capsules containing Antrodia cinnamomea fruiting body extract combined with turmeric and probiotics, administered once daily for 3 months during platinum-based chemotherapy treatment. Each capsule contains standardized amounts of Antrodia cinnamomea extract, curcumin (from turmeric), and probiotic strains.

DIETARY_SUPPLEMENTTurmeric-Probiotic Group

Capsules containing turmeric and probiotics (without Antrodia cinnamomea), same dosing schedule and appearance as experimental group.


Locations(1)

Tri-Service General Hospital

Taipei, Taiwan

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NCT07241182


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