RecruitingNot ApplicableNCT07260032

Determining the Benefits of Exercise on Cardiovascular Risk in PTSD

Using Advanced Imaging to Determine the Benefits of Exercise on Cardiovascular Risk in PTSD

Sponsor

Massachusetts General Hospital

Enrollment

10 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Disease PTSD Cardiovascular Disease Risk Factors

Summary

The purpose of this study is to use a non-invasive imaging technique called positron emission tomography/magnetic resonance imaging (PET/MRI) to investigate the effects of exercise on brain activity and arterial (blood vessel) inflammation in people with PTSD symptoms and evidence of or elevated risk for artery disease.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an exercise program can reduce cardiovascular (heart and blood vessel) risk in adults who have PTSD (post-traumatic stress disorder), since PTSD is linked to higher rates of heart disease. **You may be eligible if...** - You are between 18 and 65 years old - You have experienced trauma and have PTSD symptoms - You have signs of early or established heart/artery disease, OR you have more than 2 heart risk factors (such as high blood pressure, diabetes, high cholesterol, or active smoking) **You may NOT be eligible if...** - You have had a prior stroke or other condition making exercise unsafe - You are unable to perform the required exercise activities - You have certain unstable psychiatric or medical conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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