Liver Neoplasm Clinical Trials

26 recruitingLast updated: June 18, 2026

There are 26 actively recruiting liver neoplasm clinical trials across 19 countries. Studies span Phase 2, Not Applicable, Phase 1, Phase 3. Top locations include Taipei, Taiwan, San Francisco, California, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Liver Neoplasm Trials at a Glance

26 actively recruiting trials for liver neoplasm are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Phase 2 with 8 trials, with the heaviest enrollment activity in Taipei, San Francisco, and Boston. Lead sponsors running liver neoplasm studies include Eureka Therapeutics Inc., Beijing Tsinghua Chang Gung Hospital, and Aptamer Sciences, Inc..

Browse liver neoplasm trials by phase

Treatments under study

About Liver Neoplasm Clinical Trials

Looking for clinical trials for Liver Neoplasm? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Neoplasm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Neoplasm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 26 trials

Recruiting

Prediction Model for MINS After Major Hepatobiliary Surgery

Postoperative ComplicationsLiver NeoplasmMyocardial Injury After Noncardiac Surgery (MINS)+1 more
Beijing Tsinghua Chang Gung Hospital1,800 enrolled6 locationsNCT07335042
Recruiting
Not Applicable

Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection

Liver CancerLiver NeoplasmsHepatic Resection
Nguyen Toan Thang60 enrolled1 locationNCT07642336
Recruiting
Phase 2

Y-90 Treatment Response Using Transarterial Radioembolization

Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting
Phase 1Phase 2

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting
Phase 2

Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging

Breast CancerKidney NeoplasmsLiver Neoplasms
UNC Lineberger Comprehensive Cancer Center40 enrolled1 locationNCT07225114
Recruiting
Phase 1Phase 2

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaUnresectable Hepatocellular Carcinoma+4 more
Pfizer138 enrolled35 locationsNCT07227012
Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
HistoSonics, Inc.5,000 enrolled30 locationsNCT06486454
Recruiting
Phase 2

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

Metastatic Malignant Neoplasm in the LiverLiver and Intrahepatic Bile Duct NeoplasmPrimary Malignant Liver Neoplasm
M.D. Anderson Cancer Center140 enrolled1 locationNCT04982653
Recruiting
Not Applicable

TheraSphere Japan Pre-Market Study

Liver Neoplasms
Boston Scientific Corporation51 enrolled4 locationsNCT07377487
Recruiting

Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy

Liver Neoplasm
University of Sydney50 enrolled5 locationsNCT05169177
Recruiting
Not Applicable

Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study

Carcinoma, HepatocellularLiver NeoplasmsAdenocarcinoma+2 more
Shanghai Zhongshan Hospital17 enrolled1 locationNCT06794073
Recruiting

Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

Liver NeoplasmLiver FibrosisHBV Infection+1 more
Nanfang Hospital, Southern Medical University240 enrolled1 locationNCT07265544
Recruiting
Phase 1

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

Carcinoma, Non-Small Cell LungCarcinoma, HepatocellularNeoplasms+1 more
Aptamer Sciences, Inc.70 enrolled4 locationsNCT06687941
Recruiting

Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room

Liver NeoplasmsInguinal HerniaCholecystitis+1 more
Taipei Veterans General Hospital, Taiwan315 enrolled1 locationNCT07473687
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting

Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors

Liver Neoplasm
Central Hospital, Nancy, France90 enrolled1 locationNCT07413640
Recruiting
Phase 2

Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors

Liver Neoplasms
john eisenbrey266 enrolled1 locationNCT06261814
Recruiting
Not Applicable

Spinal Anesthesia For Enhanced Recovery After Liver Surgery

Pain, PostoperativeLiver NeoplasmsHepatectomy
University of Manitoba128 enrolled1 locationNCT03715517
Recruiting

Exploratory Blood-Based Biomarkers in TACE-Treated Hepatocellular Carcinoma

Liver NeoplasmsHepatocellular Carcinoma (HCC)
University of Belgrade15 enrolled1 locationNCT07378709
Recruiting

Biomarkers of Resiliency In Childhood Cancer Surgery

SarcomaNeuroblastomaPediatric Cancer+10 more
Mayo Clinic40 enrolled1 locationNCT06674811