Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2
Motivated Decision-Making and Performance
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
200 participants
Jul 16, 2025
INTERVENTIONAL
Conditions
Summary
This proposal aims to understand the neurobiological mechanisms of fatigue in individuals with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). This knowledge will eventually provide candidate mechanisms to target with pharmacological intervention and inform rehabilitative care for those individuals suffering from symptoms of fatigue in PASC.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Participants will perform a physically demanding task (grip force exertion task) repeatedly to induce physical fatigue.
Locations(1)
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NCT07278388