RecruitingNot ApplicableNCT07294781

Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness

CircaTime: Effects of Circadian Rhythms on Time Perception During a 36-Hour Constant Routine in Healthy Adults


Sponsor

University of Aarhus

Enrollment

30 participants

Start Date

Dec 5, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study examines how the internal body clock (circadian rhythms) influences the way healthy adults experience time, think, and feel when they stay awake for an extended period. Participants will spend about 36 hours in a controlled sleep laboratory while remaining awake the entire time. Light, posture, food intake, and activity are kept as constant as possible (a "constant routine") so that changes over time mainly reflect the body's internal clock and increasing sleepiness, rather than changes in the environment. Every two hours, participants complete a brief test battery that includes ratings of sleepiness and mood, a reaction-time task, and short tasks that assess how fast or slow time seems to pass, how accurately they can estimate time intervals, how they respond to simple decisions, and how they judge colours. Saliva samples are collected repeatedly to measure melatonin, a hormone that indicates circadian phase. By comparing changes in behaviour, perception, and melatonin levels across the 36-hour wake period, the study aims to identify when during the circadian cycle people are most vulnerable to distortions in time perception and reduced alertness. The findings may help improve scheduling of shift work and other activities that require sustained wakefulness.


Eligibility

Min Age: 23 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Constant Routine Wakefulness for people with circadian rhythm, healthy volunteers, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 23 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALConstant Routine Wakefulness

Behavioral intervention consisting of approximately 36 hours of continuous wakefulness under constant-routine conditions. Environmental factors (light level, temperature, noise) are held as constant as feasible; posture and activity are standardised; and participants receive small, isocaloric snacks at regular intervals. A repeated cognitive and perceptual test battery is administered every two hours to assess time perception, vigilance, mood, and related functions across the circadian cycle.


Locations(1)

Aarhus University, Department of Psychology and Behavioural Sciences

Aarhus, Denmark

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NCT07294781


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