Circadian Rhythm Clinical Trials

18 recruiting

Circadian Rhythm Trials at a Glance

42 actively recruiting trials for circadian rhythm are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Portland, Aarhus, and Fort Collins. Lead sponsors running circadian rhythm studies include Oregon Health and Science University, University of Aarhus, and Colorado State University.

Browse circadian rhythm trials by phase

Treatments under study

About Circadian Rhythm Clinical Trials

Looking for clinical trials for Circadian Rhythm? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Circadian Rhythm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Circadian Rhythm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 42 trials

Recruiting
Not Applicable

Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Circadian Rhythm Disorders
West Virginia University80 enrolled1 locationNCT04578249
Recruiting
Not Applicable

Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

SleepCircadian RhythmCannabis Use
University of Pittsburgh180 enrolled1 locationNCT06743373
Recruiting
Not Applicable

Mind After Midnight

Suicidal IdeationSleep DeprivationSleep Wake Disorders+1 more
University of Arizona90 enrolled1 locationNCT07438912
Recruiting
Not Applicable

Sleep and Circadian Mechanisms in Hypertension

Cardiovascular DiseasesHypertensionSleep+2 more
Oregon Health and Science University32 enrolled1 locationNCT05184933
Recruiting
Not Applicable

Feasibility of Wearables in Dementia Care in Rural Taiwan

Circadian RhythmAlzheimer's DementiaNeuropsychiatric Symptoms Related to Neurodegenerative Disease+2 more
China Medical University Hospital20 enrolled1 locationNCT07249918
Recruiting
Not Applicable

Dietary Impact on Sleep, Rhythms and Related Physiology

SleepCircadian RhythmDiet Interventions
Uppsala University24 enrolled1 locationNCT07138313
Recruiting
Not Applicable

Nighttime Synchrony of Your Nutrition and Circadian Health

SleepCircadian RhythmLifestyle Factors+5 more
University of Utah120 enrolled1 locationNCT07329283
Recruiting
Not Applicable

The Effect of a Continuous 1-Hour Time Delay on Circadian Rhythms

SleepCircadian RhythmsTime Perception
University of Aarhus40 enrolled1 locationNCT07317349
Recruiting
Not Applicable

Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm

SleepFatigueHumans+9 more
Region Skane300 enrolled1 locationNCT05107947
Recruiting
Not Applicable

Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness

Healthy VolunteersCircadian RhythmSleep Deprivation+1 more
University of Aarhus30 enrolled1 locationNCT07294781
Recruiting
Not Applicable

Circadian Timing and Time Perception in Healthy Adults

Circadian RhythmTime Perception
University of Aarhus128 enrolled1 locationNCT07292597
Recruiting
Not Applicable

Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers

Metabolic DiseaseBlood PressureInsulin Sensitivity+1 more
Colorado State University50 enrolled1 locationNCT06550115
Recruiting

Translation and Validation of the French Version of the Sleep Regularity Questionnaire: a New Tool to Address the the Challenge of Sleep Health

Circadian Rhythm DisordersChronic Insomnia Disorder
University Hospital, Bordeaux50 enrolled1 locationNCT06727448
Recruiting
Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Sleep Wake DisordersSleep Disorders, Circadian RhythmChronobiology Disorders
Vanda Pharmaceuticals70 enrolled17 locationsNCT04652882
Recruiting
Not Applicable

Food and Circadian Timing

Circadian RhythmDiet, High-Fat
Oregon Health and Science University14 enrolled1 locationNCT04743271
Recruiting
Not Applicable

The Influence of Sleep on Cardiovascular Outcomes

Circadian Rhythm
Oregon Health and Science University30 enrolled1 locationNCT06535178
Recruiting
Not Applicable

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

Critical IllnessSleep DeprivationCircadian Rhythm Sleep Disorder, Unspecified
Yale University160 enrolled2 locationsNCT05551325
Recruiting

Night Shift Work and Biomarkers of Obesity Risk in Hospital and Industry Workers

ObesityShift-work DisorderCircadian Rhythm Disorders
University of Vienna1,000 enrolled1 locationNCT06288568
Recruiting
Not Applicable

Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers

Cardiovascular DiseasesCircadian Rhythm Sleep Disorder, Shift Work TypeCholesterol Level, High
Fundació Eurecat22 enrolled2 locationsNCT06422741
Recruiting
Not Applicable

Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

HypertensionCircadian RhythmYoung Adults+1 more
Freda Patterson30 enrolled1 locationNCT07049783