Sleep Deprivation Clinical Trials

28 recruiting

Sleep Deprivation Trials at a Glance

33 actively recruiting trials for sleep deprivation are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Boston, Salt Lake City, and Columbus. Lead sponsors running sleep deprivation studies include Beth Israel Deaconess Medical Center, University of Utah, and Critical Care Research Group.

Browse sleep deprivation trials by phase

Treatments under study

About Sleep Deprivation Clinical Trials

Looking for clinical trials for Sleep Deprivation? There are currently 28 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep Deprivation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep Deprivation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Not Applicable

Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

Sleep Deprivation
University of Guelph30 enrolled1 locationNCT06679543
Recruiting

Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators

Cognitive ChangeSleepSleep Deprivation
Beth Israel Deaconess Medical Center75 enrolled1 locationNCT05026541
Recruiting
Not Applicable

The Effect of Sleep Loss on Emotion Regulation

InsomniaSleepSleep Deprivation
Beth Israel Deaconess Medical Center90 enrolled1 locationNCT05393830
Recruiting
Not Applicable

Mind After Midnight

Suicidal IdeationSleep DeprivationSleep Wake Disorders+1 more
University of Arizona90 enrolled1 locationNCT07438912
Recruiting
Not Applicable

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

Sleep Deprivation
Pennington Biomedical Research Center100 enrolled1 locationNCT06070194
Recruiting
Not Applicable

Nighttime Synchrony of Your Nutrition and Circadian Health

SleepCircadian RhythmLifestyle Factors+5 more
University of Utah120 enrolled1 locationNCT07329283
Recruiting
Not Applicable

Effects of Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD) on Memory and Cognitive Function in Adults With Sleep Deprivation: A Proof-of-Concept Study

Sleep Deprivation
Tao Liu30 enrolled1 locationNCT07084701
Recruiting
Not Applicable

Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness

Healthy VolunteersCircadian RhythmSleep Deprivation+1 more
University of Aarhus30 enrolled1 locationNCT07294781
Recruiting
Not Applicable

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

SleepSleep Deprivation
Yuhui Qiu60 enrolled1 locationNCT07085754
Recruiting

Immune Status After Being on Call for 24 Hrs

Sleep Deprivation
University of Chicago60 enrolled1 locationNCT06636318
Recruiting
Not Applicable

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

Critical IllnessSleep DeprivationCircadian Rhythm Sleep Disorder, Unspecified
Yale University160 enrolled2 locationsNCT05551325
Recruiting
Not Applicable

Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)

Sleep DeprivationCaffeine
University of Arizona180 enrolled2 locationsNCT05588934
Recruiting
Not Applicable

Menstrual-phase-dependent Differences in Response to Sleep Loss

Sleep Deprivation
Brigham and Women's Hospital100 enrolled1 locationNCT05381532
Recruiting
Not Applicable

The Peripheral Blood Multi-Omics Study on Sleep Loss

Cognitive DeclineAlzheimer DiseaseAging+3 more
First Affiliated Hospital of Zhejiang University60 enrolled1 locationNCT06492109
Recruiting
Not Applicable

Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep

Sleep DeprivationMental Competency
U.S. Army Medical Research and Development Command40 enrolled1 locationNCT02945501
Recruiting
Not Applicable

Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction

Sleep Deprivation
Ohio State University60 enrolled1 locationNCT05519644
Recruiting
Not Applicable

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

Sleep DeprivationNutritional Intervention
Ohio State University60 enrolled1 locationNCT06075914
Recruiting
Not Applicable

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

InsomniaSleepSleep Disturbance+4 more
Rhode Island Hospital55 enrolled1 locationNCT06737055
Recruiting
Not Applicable

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

SleepType 2 DiabetesOverweight and Obesity+6 more
University of Utah70 enrolled1 locationNCT06180837
Recruiting
Not Applicable

Biomarkers of Increased Free Living Sleep Time

Sleep DeprivationInsufficient Sleep SyndromeSleep Wake Disorders
University of Utah46 enrolled1 locationNCT04214184