RecruitingNCT07334457

Study of Platelet Population Changes Under Circulatory Support With ECMO


Sponsor

University Hospital, Strasbourg, France

Enrollment

75 participants

Start Date

Mar 11, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital.
  • Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.

Exclusion Criteria3

  • Subject who has expressed their opposition to participating in the study.
  • Subject under legal protection.
  • Subject under guardianship or curatorship.

Locations(1)

Service d'anesthésie-réanimation - CHU de Strasbourg - France

Strasbourg, France

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NCT07334457


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