RecruitingNCT07334457

Study of Platelet Population Changes Under Circulatory Support With ECMO

Sponsor

University Hospital, Strasbourg, France

Enrollment

75 participants

Start Date

Mar 11, 2025

Study Type

OBSERVATIONAL

Conditions

Respiratory Failure Cardiac Failure

Summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how platelets (blood cells involved in clotting) change in patients who are placed on ECMO — a life support machine that takes over the work of the heart and/or lungs in critically ill patients. The goal is to better understand how ECMO affects the blood. **You may be eligible if...** - You are 18 or older - You are being treated in the intensive care unit (ICU) at Strasbourg University Hospital - You have been placed on veno-arterial or veno-venous ECMO within the past 24 hours **You may NOT be eligible if...** - You have stated that you do not wish to participate - You are under legal protection, guardianship, or curatorship Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Service d'anesthésie-réanimation - CHU de Strasbourg - France

Strasbourg, France

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NCT07334457

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