RecruitingNot ApplicableNCT07463859

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus: A Randomized Clinical Trial


Sponsor

University of Sao Paulo

Enrollment

32 participants

Start Date

Apr 2, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in reducing halitosis in individuals with periodontal disease and type 2 diabetes mellitus. The main question it aims to answer is: aPDT treatment is more effective in treating halitosis? aPDT treatment is more effective in periodontitis? Researchers will compare aPDT treatment to conventional treatment (scaling and root planning and tongue scraper) to see if aPDT has additional effects in reducing halitosis and improving periodontal health. * Participants will be asked to visit the clinic once a week for exam and treatment during 1 month. * After active treatment they will be asked to come to maintenance and control visits once a month until 6 months.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether combining standard gum disease treatment with a light-based therapy (called antimicrobial photodynamic therapy) can reduce bad breath (halitosis) in people with both type 2 diabetes and serious gum disease. Both conditions affect mouth bacteria, and researchers want to see if the added treatment improves outcomes. **You may be eligible if...** - You have been diagnosed with type 2 diabetes (per WHO criteria) - You have stage 3 or 4 periodontitis (severe gum disease) - You have not received gum disease treatment in the past 12 months - You have at least 20 remaining teeth **You may NOT be eligible if...** - You smoke - You have an alcohol dependence - You are pregnant or breastfeeding - You have kidney disease - You take medications that affect the gums (such as certain blood pressure drugs) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREScaling and root planing

Mechanical removal of biofilm in periodontal pockets and tongue

PROCEDUREPhotodynamic Therapy with Conventional Methylene Blue

Antimicrobial photodynamic therapy in periodontal pockets and tongue


Locations(1)

Bauru School of Dentistry

Bauru, São Paulo, Brazil

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NCT07463859


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