Performance of the Treatment of Periodontitis According to the Bioperio® Protocol
Performance of the Treatment of Periodontitis According to the Bioperio® Protocol: a Prospective Cohort Study
University of Pisa
5,000 participants
Dec 5, 2023
OBSERVATIONAL
Conditions
Summary
This multicenter, prospective, single-arm observational study evaluated the clinical performance of the Bioperio® protocol, a standardized, patient-centered framework for managing periodontitis. The protocol combined professional supra-gingival scaling, oral hygiene instruction and motivation, full-mouth subgingival instrumentation, and-in Stage III/IV cases-adjunctive enamel matrix derivative application in deep pockets.
Eligibility
Inclusion Criteria4
- Confirmed diagnosis of periodontitis (proximal attachment loss in ≥2 non-adjacent teeth)
- No previous treatment for periodontitis
- Systemically healthy or with well-controlled chronic medical conditions
- Willingness to participate in the study and comply with the follow-up schedule
Exclusion Criteria5
- Pregnancy or breastfeeding
- Patients previously treated for periodontitis
- Poorly controlled systemic conditions
- Refusal to participate
- Patients who did not complete the proposed treatment plan
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Interventions
Non surgical periodontal therapy performed with ultrasonics and manual instruments. In patients affected by stages III-IV periodontitis, the adjunctive usage of wound healing enhancers will be applied in sites with PPD \>5 mm.
Patients will be motivated and instructed to improve their daily home dental plaque control through the usage of interdental devices and electric toothbrush.
In some selected patients, whose periodontal defects will not heal despite consecutive non surgical interventions, periodontal surgical treatment, with or without regenerative devices, will be implemented.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07507474