RecruitingNCT07473375

Indicators Affecting PVT Recanalization

Indicators Affecting Portal Vein Thrombosis Recanalization in Cirrhosis With Gastroesophageal Varices

Sponsor

Shanghai Zhongshan Hospital

Enrollment

1,500 participants

Start Date

Jan 1, 2017

Study Type

OBSERVATIONAL

Conditions

Cirrhosis Portal Hypertension Related to Cirrhosis Portal Vein Thrombosis Portal Hypertension, Noncirrhotic

Summary

This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at factors that affect whether a blood clot in the portal vein (the main vein supplying the liver) can dissolve or clear up (called recanalization) in patients who have liver cirrhosis. Researchers hope to identify predictors that help doctors make better treatment decisions. **You may be eligible if...** - You have been diagnosed with liver cirrhosis - You have been confirmed to have varicose veins in the esophagus or stomach (gastroesophageal varices) seen on endoscopy - You have been diagnosed with a portal vein blood clot (PVT) confirmed by imaging (CTA) at admission **You may NOT be eligible if...** - You have liver cancer (hepatocellular carcinoma) - You have another cancer outside the liver - You have had a liver transplant or a TIPS procedure (a shunt placed in the liver) - Information about your anticoagulation (blood thinning) treatment is not available - You have a condition called cavernous transformation of the portal vein Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.