RecruitingPhase 2NCT07551583

Phase II Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHL

A Phase II Single Arm Study to Evaluate Safety and Preliminary Efficacy of Nivolumab Plus AVD in Pediatric, Adolescent, And Young Adult Patients With Newly Diagnosed Early-stage Non-bulky Classical Hodgkin Lymphoma


Sponsor

M.D. Anderson Cancer Center

Enrollment

15 participants

Start Date

Aug 19, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical research study is to learn if nivolumab plus AVD (doxorubicin, vinblastine, and dacarbazine) can help to control newly diagnosed early-stage non-bulky cHL in pediatric, adolescent, and young adult patients. The safety of this drug combination will also be studied.


Eligibility

Min Age: 2 YearsMax Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dacarbazine, a drug called Doxorubicin Hydrochloride, and others for people with hodgkin lymphoma. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNivolumab

Given by IV

DRUGDoxorubicin Hydrochloride

Given by IV

DRUGVinblastine

Given by IV

DRUGDacarbazine

Given by IV


Locations(1)

UT MD Anderson

Houston, Texas, United States

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NCT07551583


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