RISS Versus SPSIP Block in Modified Radical Mastectomy
Comparison of Rhomboid Intercostal-Subserratus Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia and Dermatomal Spread After Modified Radical Mastectomy: A Randomized Double-Blind Trial
Ferit Yetik
80 participants
Jun 19, 2026
INTERVENTIONAL
Conditions
Summary
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior intercostal plane (SPSIP) block in patients undergoing modified radical mastectomy. Postoperative pain scores, opioid consumption, rescue analgesic requirements, block-related complications, and quality of recovery outcomes will be evaluated.
Eligibility
Inclusion Criteria4
- Female patients aged 18-75 years
- ASA physical status I-III
- Scheduled for elective unilateral modified radical mastectomy with axillary dissection under general anesthesia
- Provision of written informed consent
Exclusion Criteria10
- Anticoagulant therapy
- Bleeding diathesis
- Known allergy to local anesthetics or opioids
- Infection at the block application site or previous surgery in the block area
- Cognitive impairment preventing NRS assessment
- Pregnancy or lactation
- Chronic opioid use
- Severe hepatic or renal failure
- Refusal to participate in the study
- Technical inability to perform the block or failed block
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Interventions
Ultrasound-guided rhomboid intercostal-subserratus plane block performed before modified radical mastectomy for postoperative analgesia.
Ultrasound-guided serratus posterior superior intercostal plane block performed before modified radical mastectomy for postoperative analgesia.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07659990