RecruitingNot ApplicableNCT07681973

Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training


Sponsor

The Cleveland Clinic

Enrollment

52 participants

Start Date

Dec 9, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss. The impact of a 3-month olfactory training program on smell function, immunological changes, and mental health in patients with smell loss will be evaluated. The primary purpose of this study is to investigate tissue and blood samples to identify molecules that may be related to smell loss, ultimately aiming to develop future treatments for this condition and correlate with cognition.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Smell Training for people with chronic rhinosinusitis (crs) and smell loss. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSmell Training

Patients experiencing loss of smell from chronic rhinosinusitis (CRS)will undergo smell training.


Locations(1)

The Cleveland Clinic

Cleveland, Ohio, United States

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NCT07681973


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