Phase 3 ACC Clinical Trials
42 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 42 trials
Recruiting
Phase 2Phase 3
Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH
Mucopolysaccharidosis IIIMPS IIIASanfilippo Syndrome+1 more
Ultragenyx Pharmaceutical Inc36 enrolled5 locationsNCT02716246
Recruiting
Phase 2Phase 3
Naltrexone for Overdose Prevention
Overdose Accidental
University of California, San Francisco100 enrolled1 locationNCT06633900
Recruiting
Phase 3
Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion
Acute Cerebrovascular AccidentBasilar Artery OcclusionStroke Due to Basilar Artery Occlusion
The First Affiliated Hospital of University of Science and Technology of China338 enrolled1 locationNCT05827042
Recruiting
Phase 3
Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
Non-small Cell Lung CancerAdvanced Non-Small Cell Lung CancerMetastatic Non Small Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.480 enrolled74 locationsNCT07185997
Recruiting
Phase 3
Semaglutide for Smoking Cessation in Patients With Diabetes
Diabetes Mellitus, Type 2Tobacco DependenceNicotine Addiction
Ottawa Heart Institute Research Corporation100 enrolled1 locationNCT07059377
Recruiting
Phase 3
Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement
Opioid UseTobacco UsePolysubstance Abuse
Rutgers, The State University of New Jersey420 enrolled2 locationsNCT06033599
Recruiting
Phase 3
A Study to Evaluate Immunogenicity and Safety After the First and Second Doses of MG1111 (BARYCELA Inj.) in Healthy Children Aged 12 Months to 12 Years
Varicella (Chickenpox)Chickenpox Vaccine
GC Biopharma Corp474 enrolled1 locationNCT07054099
Recruiting
Phase 3
Shingrix in Renal Transplant Recipients
Kidney FailureKidney TransplantationKidney Failure, Chronic+2 more
University of Colorado, Denver132 enrolled4 locationsNCT04128189
Recruiting
Phase 3
Cannabis-Tobacco Co-Use Treatment Study
Tobacco Use DisorderTobacco Use CessationCannabis Use+2 more
Medical University of South Carolina200 enrolled1 locationNCT06883162
Recruiting
Phase 2Phase 3
Study of Cannabidiol in Sanfilippo Syndrome
Mucopolysaccharidosis IIISanfilippo Syndrome
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center35 enrolled1 locationNCT06333041
Recruiting
Phase 2Phase 3
Minocycline in Stroke Study at Maimonides
Cerebrovascular Accident (Stroke)StrokeMortality+4 more
Joyce Chen1,164 enrolled1 locationNCT07237048
Recruiting
Phase 3
Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination
Pneumococcal Vaccines
Vaxcyte, Inc.720 enrolled30 locationsNCT07425392
Recruiting
Phase 3
Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation
Tobacco Dependence
University of Alabama at Birmingham400 enrolled1 locationNCT03912194
Recruiting
Phase 3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc.400 enrolled138 locationsNCT05566795
Recruiting
Phase 3
Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus
Cholera Vaccination
International Vaccine Institute2,824 enrolled5 locationsNCT07304284
Recruiting
Phase 3
Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease
Tobacco SmokingAlcohol-Related Disorders
VA Office of Research and Development270 enrolled1 locationNCT07039175
Recruiting
Phase 3
Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial)
VaccinationInfluenza (Pandemic)Avian Influenza
University Health Network, Toronto120 enrolled1 locationNCT07240558
Recruiting
Phase 3
RSV Vaccine in Transplant Recipients
Immune SuppressionVaccine Response ImpairedRespiratory Syncytial Virus Infections
University Health Network, Toronto100 enrolled1 locationNCT06593210
Recruiting
Phase 3
CAR-T Long Term Follow Up (LTFU) Study
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
Novartis Pharmaceuticals1,400 enrolled118 locationsNCT02445222
Recruiting
Phase 3
A Study to Evaluate the Immunogenicity and Safety of an EV71 Vaccine (Envacgen®) in Children Aged 6 to <10 Years Compared to Children Aged 2 to <6 Years
Enterovirus 71 Inactivated Vaccine
Medigen Vaccine Biologics Corp.378 enrolled3 locationsNCT07178522