Phase 2 ACC Clinical Trials

51 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 51 trials

Recruiting
Phase 1Phase 2

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

Aggressive NK-cell LeukemiaLGLL - Large Granular Lymphocytic LeukemiaPrimary Cutaneous Gamma-Delta T-Cell Lymphoma+10 more
Dren Bio200 enrolled37 locationsNCT05475925
Recruiting
Phase 2Phase 3

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Mucopolysaccharidosis IIIMPS IIIASanfilippo Syndrome+1 more
Ultragenyx Pharmaceutical Inc36 enrolled5 locationsNCT02716246
Recruiting
Phase 2

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Colorectal, CancerCholangiocarcinomaColorectal Neoplasms+10 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05286814
Recruiting
Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting
Phase 2Phase 3

Naltrexone for Overdose Prevention

Overdose Accidental
University of California, San Francisco100 enrolled1 locationNCT06633900
Recruiting
Phase 2

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

InsomniaTobacco UseTobacco Cessation
Yale University114 enrolled2 locationsNCT06609369
Recruiting
Phase 2

Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS

Renal StonesRetrograde Intrarenal SurgeryUreteral Access Sheath Placement
Beni-Suef University322 enrolled3 locationsNCT07623876
Recruiting
Phase 2

Personalized NK Cell Therapy in CBT

Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia+23 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02727803
Recruiting
Phase 2

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+5 more
M.D. Anderson Cancer Center90 enrolled1 locationNCT03263572
Recruiting
Phase 2

Strengthening HPV Immunization Through EPI Leveraged Delivery

HPV Vaccine
International Vaccine Institute115 enrolled1 locationNCT07377656
Recruiting
Phase 2

Infant Malaria Vaccine Schedule Optimization

Malaria Vaccines
PATH964 enrolled2 locationsNCT06879327
Recruiting
Phase 2

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

Myelodysplastic/Myeloproliferative NeoplasmPolycythemia VeraPrimary Myelofibrosis+5 more
National Cancer Institute (NCI)62 enrolled31 locationsNCT06661915
Recruiting
Phase 2

Informing Oral Nicotine Pouch Regulations to Promote Public Health

Tobacco-Related Carcinoma
Ohio State University Comprehensive Cancer Center160 enrolled1 locationNCT06315881
Recruiting
Phase 2

Accelerated dTMS Smoking Cessation

Tobacco Use DisorderAddiction Nicotine
Waypoint Centre for Mental Health Care40 enrolled2 locationsNCT07292883
Recruiting
Phase 1Phase 2

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Solid TumorsAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl70 enrolled23 locationsNCT03934372
Recruiting
Phase 2

Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

Adrenocortical CarcinomaACCMetastatic Adrenocortical Carcinoma
Memorial Sloan Kettering Cancer Center12 enrolled7 locationsNCT06066333
Recruiting
Phase 2

Cannabidiol for Reducing Cigarette Use

Tobacco Use DisorderTobacco DependenceTobacco Smoking
University of California, Los Angeles120 enrolled1 locationNCT06218056
Recruiting
Phase 2Phase 3

Study of Cannabidiol in Sanfilippo Syndrome

Mucopolysaccharidosis IIISanfilippo Syndrome
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center35 enrolled1 locationNCT06333041
Recruiting
Phase 2

Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children

Cholera Vaccination
International Vaccine Institute390 enrolled1 locationNCT07509047
Recruiting
Phase 2Phase 3

Minocycline in Stroke Study at Maimonides

Cerebrovascular Accident (Stroke)StrokeMortality+4 more
Joyce Chen1,164 enrolled1 locationNCT07237048