Phase 2 ACC Clinical Trials
44 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 44 trials
Recruiting
Phase 2
A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
Myelodysplastic/Myeloproliferative NeoplasmPolycythemia VeraPrimary Myelofibrosis+5 more
National Cancer Institute (NCI)62 enrolled30 locationsNCT06661915
Recruiting
Phase 2
Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer
Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting
Phase 2Phase 3
Naltrexone for Overdose Prevention
Overdose Accidental
University of California, San Francisco100 enrolled1 locationNCT06633900
Recruiting
Phase 2
Informing Oral Nicotine Pouch Regulations to Promote Public Health
Tobacco-Related Carcinoma
Ohio State University Comprehensive Cancer Center160 enrolled1 locationNCT06315881
Recruiting
Phase 2Phase 3
Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH
Mucopolysaccharidosis IIIMPS IIIASanfilippo Syndrome+1 more
Ultragenyx Pharmaceutical Inc36 enrolled5 locationsNCT02716246
Recruiting
Phase 1Phase 2
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Solid TumorsAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl70 enrolled23 locationsNCT03934372
Recruiting
Phase 2
Accelerated dTMS Smoking Cessation
Tobacco Use DisorderAddiction Nicotine
Waypoint Centre for Mental Health Care40 enrolled2 locationsNCT07292883
Recruiting
Phase 2
Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma
Adrenocortical CarcinomaACCMetastatic Adrenocortical Carcinoma
Memorial Sloan Kettering Cancer Center12 enrolled7 locationsNCT06066333
Recruiting
Phase 2
Cannabidiol for Reducing Cigarette Use
Tobacco Use DisorderTobacco DependenceTobacco Smoking
University of California, Los Angeles120 enrolled1 locationNCT06218056
Recruiting
Phase 2Phase 3
Study of Cannabidiol in Sanfilippo Syndrome
Mucopolysaccharidosis IIISanfilippo Syndrome
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center35 enrolled1 locationNCT06333041
Recruiting
Phase 2
Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children
Cholera Vaccination
International Vaccine Institute390 enrolled1 locationNCT07509047
Recruiting
Phase 2Phase 3
Minocycline in Stroke Study at Maimonides
Cerebrovascular Accident (Stroke)StrokeMortality+4 more
Joyce Chen1,164 enrolled1 locationNCT07237048
Recruiting
Phase 2
Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant for Patients With Accelerated and Blast Phase Myeloproliferative Neoplasms
Accelerated Phase Myeloproliferative NeoplasmBlast Phase Myeloproliferative Neoplasm
University of Washington27 enrolled1 locationNCT07148947
Recruiting
Phase 2
Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia
Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+5 more
M.D. Anderson Cancer Center90 enrolled1 locationNCT03263572
Recruiting
Phase 2
Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD
Tobacco Use Disorder
VA Office of Research and Development50 enrolled1 locationNCT05723588
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine
Herpes ZostermRNA Vaccine
Sinovac Biotech Co., Ltd519 enrolled1 locationNCT07400003
Recruiting
Phase 2
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
VapingCannabis UseCannabis Smoking+3 more
University of California, San Francisco48 enrolled1 locationNCT05999383
Recruiting
Phase 1Phase 2
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaAcute Lymphoid Leukemia+4 more
University of Florida40 enrolled4 locationsNCT05322850
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide Vaccines for Solid Tumors
Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled2 locationsNCT07002203
Recruiting
Phase 2
Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity
Smoking CessationTobacco Use Disorder
University of California, Los Angeles64 enrolled1 locationNCT06617312