ACC Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about ACC clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 82 trials

Recruiting
Phase 1

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Adrenocortical Carcinoma (ACC)Carcinoma, AdrenocorticalCarcinoma, Adrenal Cortical+2 more
National Cancer Institute (NCI)32 enrolled1 locationNCT06487481
Recruiting
Phase 4

Smoking Cessation and Menstrual Cycle Phase

Smoking CessationSubstance Use DisordersNicotine Dependence+2 more
Centre for Addiction and Mental Health1,200 enrolled1 locationNCT05515354
Recruiting
Not Applicable

ACT Lung Health Intervention: Phase Two

Smoking CessationSmoking BehaviorsSmoking, Tobacco+2 more
Dana-Farber Cancer Institute50 enrolled2 locationsNCT06945120
Recruiting
Phase 1Phase 2

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

Aggressive NK-cell LeukemiaLGLL - Large Granular Lymphocytic LeukemiaPrimary Cutaneous Gamma-Delta T-Cell Lymphoma+10 more
Dren Bio69 enrolled37 locationsNCT05475925
Recruiting
Not Applicable

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

ObesityHypertensionOverweight+4 more
Universidad Católica San Antonio de Murcia220 enrolled1 locationNCT07447362
Recruiting
Not Applicable

Expanded Social Network Recruitment to HIV Testing (E-SNRHT) Intervention to Locate Undiagnosed Cases and Reduce HIV-related Stigma

HIV-related StigmaUndiagnosed HIV InfectionPopulations That Are Reluctant to Test for HIV+3 more
University of Illinois at Chicago2,480 enrolled1 locationNCT06857071
Recruiting
Phase 2

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+5 more
M.D. Anderson Cancer Center90 enrolled1 locationNCT03263572
Recruiting
Phase 2

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Colorectal, CancerCholangiocarcinomaColorectal Neoplasms+10 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05286814
Recruiting
Not Applicable

Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis

Accuracy of Artificial Intelligence in Fixed Dental Prosthesis Design
October University for Modern Sciences and Arts1,000 enrolled1 locationNCT07432165
Recruiting

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Esophageal CancerChemoradiationPneumococcal Vaccine+1 more
M.D. Anderson Cancer Center80 enrolled1 locationNCT06181656
Recruiting
Phase 2

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

Tobacco Use Disorder
VA Office of Research and Development50 enrolled1 locationNCT05723588
Recruiting
Not Applicable

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

Chronic Kidney DiseasesArteriovenous FistulaVascular Access Complication+7 more
VenoStent600 enrolled28 locationsNCT06001827
Recruiting
Phase 3

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Non-small Cell Lung CancerAdvanced Non-Small Cell Lung CancerMetastatic Non Small Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.480 enrolled23 locationsNCT07185997
Recruiting
Phase 4

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

Tobacco Dependence
Johns Hopkins University30 enrolled1 locationNCT07220356
Recruiting
Phase 2

Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

Adrenocortical CarcinomaACCMetastatic Adrenocortical Carcinoma
Memorial Sloan Kettering Cancer Center12 enrolled7 locationsNCT06066333
Recruiting
Not Applicable

Pivotal Study of the Velocity™ pAVF System

Chronic Kidney DiseaseEnd Stage Renal Disease (ESRD)Hemodialysis Access+1 more
Venova Medical126 enrolled10 locationsNCT07153939
Recruiting
Not Applicable

Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

HypertensionType 2 Diabetes Mellitus (T2DM)Tobacco Smoking
Johns Hopkins Bloomberg School of Public Health2,070 enrolled1 locationNCT06740708
Recruiting
Not Applicable

Health Warnings and Counseling for Smoking Cessation

HypertensionNon Communicable Chronic DiseasesTobacco Cessation+1 more
Hitotsubashi University5,052 enrolled1 locationNCT07098065
Recruiting
Not Applicable

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

HIV InfectionTobacco-Related Carcinoma
AIDS Malignancy Consortium100 enrolled11 locationsNCT04949464
Recruiting
Not Applicable

Single-Needle Distal Return for Long-Term Arteriovenous Fistula Care

Hemodialysis AccessArteriovenous FistulaArteriovenous Fistula Cannulation+2 more
Suzhou Municipal Hospital of Anhui Province100 enrolled1 locationNCT07372027