Phase 4 ACC Clinical Trials

52 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 52 trials

Recruiting
Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use DisorderNicotine DependenceCigarette Smoking
University of Oklahoma80 enrolled1 locationNCT05587361
Recruiting
Phase 4

Smoking Cessation and Menstrual Cycle Phase

Smoking CessationSubstance Use DisordersNicotine Dependence+2 more
Centre for Addiction and Mental Health1,200 enrolled1 locationNCT05515354
Recruiting
Phase 4

Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya

Cholera Vaccination
Albert B. Sabin Vaccine Institute1,071 enrolled1 locationNCT07487077
Recruiting
Phase 4

Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy

PregnancyHealthyRSV+1 more
Canadian Immunization Research Network60 enrolled4 locationsNCT07097012
Recruiting
Phase 4

Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation

Tobacco
Ottawa Heart Institute Research Corporation150 enrolled1 locationNCT06832085
Recruiting
Phase 4

6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health

GingivitisDental Plaque Accumulation
Colgate Palmolive90 enrolled1 locationNCT07414173
Recruiting
Phase 4

CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

Critical IllnessCritical Care, Intensive CareFluid and Electrolyte Imbalance+2 more
University Hospital, Antwerp640 enrolled4 locationsNCT07189091
Recruiting
Phase 4

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

Tobacco Dependence
Johns Hopkins University30 enrolled1 locationNCT07220356
Recruiting
Phase 4

Investigating Gender and Sex Differences in Immune Responses Through Vaccination of Transgender and Cisgender Persons

VaccinationTransgender PersonsMeningococcal Meningitis, Serogroup B+1 more
University Ghent250 enrolled1 locationNCT06832514
Not Yet Recruiting
Phase 4

Optimal Timing for Adolescent Meningococcal B vaccination schedule (BOOST MenB study)

Meningococcal immunityImmune Response to meningococcal vaccination
University of Adelaide284 enrolled1 locationACTRN12625001444471
Recruiting
Phase 4

Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial

Tobacco Use DisorderPsychiatric DisorderNicotine Dependence
Centre for Addiction and Mental Health40 enrolled1 locationNCT06534047
Recruiting
Phase 4

Comparing Dynamic Navigation to Static Navigation in the Implant Placement

Healthy AdultsDental ImplantAccuracy
Ain Shams University20 enrolled1 locationNCT07291336
Recruiting
Phase 4

Antibiotics and Vaccine Immune Responses Study

Vaccine Response Impaired
South Australian Health and Medical Research Institute348 enrolled1 locationNCT06148025
Recruiting
Phase 4

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

Tobacco DependenceTobacco Use CessationTobacco Use+2 more
University of California, San Francisco150 enrolled1 locationNCT07148232
Not Yet Recruiting
Phase 4

Immune Effects of Respiratory Syncytial Virus (RSV) Vaccination in Older Adults

Response to vaccinationDepressionStress+1 more
Tasmanian Health Service120 enrolled1 locationACTRN12625001211459
Recruiting
Phase 4

Addiction Potential of Very Low Nicotine Filtered Little Cigars

Smoking (Tobacco) Addiction
Ohio State University Comprehensive Cancer Center50 enrolled1 locationNCT06630728
Recruiting
Phase 4

Persistence of Immune Response Six Years After One Dose of 9vHPV Vaccine Among Male and Female Students

HPV Vaccine
Canadian Immunization Research Network300 enrolled1 locationNCT07156084
Recruiting
Phase 4

Characterizing the Human Airway Immune Response to FluMist Vaccination

Healthy Young AdultsInfluenza VaccinesInfluenza Vaccine Response
Washington University School of Medicine30 enrolled1 locationNCT07177417
Recruiting
Phase 4

Smoking Cessation Program in the Construction Sector

Smoking CessationTobacco Use CessationTobacco Smoking
University of Miami608 enrolled1 locationNCT06098144
Recruiting
Phase 4

Impact of Semaglutide on Tobacco Use and Related Health Behaviors

Tobacco Use
University of Oklahoma40 enrolled1 locationNCT06986993