Phase 4 ache Clinical Trials
19 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–19 of 19 trials
Not Yet Recruiting
Phase 4
Sphenopalatine Nerve Ganglion Block for Acute Benign Headaches in the Emergency Department: A Pilot Randomized Controlled Trial
benign headaches (e.g. migraine)
The Ottawa Hospital Research Institute175 enrolled1 locationACTRN12626000229370
Recruiting
Phase 4
Remimazolam for Bronchoscopy in High-Risk Patients
Pulmonary NodulePulmonary InfectionPhthisis+2 more
First Affiliated Hospital of Zhejiang University360 enrolled2 locationsNCT07395596
Recruiting
Phase 4
Remifentanil Versus Rocuronium for Optimizing Video Laryngoscopy-assisted Tracheal Intubation
Video LaryngoscopyRemifentanilRocuronium+1 more
Nordsjaellands Hospital2,648 enrolled2 locationsNCT06564857
Recruiting
Phase 4
A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia
Clinical Characteristics and Treatment Outcomes of Malignant Tumor CachexiaMulticenter Observational Study
Changchun GeneScience Pharmaceutical Co., Ltd.495 enrolled1 locationNCT07243379
Recruiting
Phase 4
Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage
HeadacheAneurysmal Subarachnoid Hemorrhage (aSAH)
Wright State University20 enrolled1 locationNCT07116408
Recruiting
Phase 4
Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)
Refractory Chronic Cluster Headache
University Hospital, Clermont-Ferrand90 enrolled14 locationsNCT04814381
Recruiting
Phase 4
Acute Migraine Treatment in the ED With Gepants
Migraine Headaches
Icahn School of Medicine at Mount Sinai100 enrolled1 locationNCT06985342
Recruiting
Phase 4
Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals
migraine headacheMigraineMigraine Disease+2 more
Ain Shams University120 enrolled1 locationNCT07022496
Recruiting
Phase 4
Effect of Tramadol on Postoperative Sore Throat After General Anesthesia
Thyroid surgeryPost-operative Sore ThroatIntubation Intratracheal
Affiliated Cancer Hospital of Shantou University Medical College168 enrolled1 locationNCT04991493
Completed
Phase 3Phase 4
A double-blind randomised controlled study to evaluate the effectiveness of orally-dosed Palmitoylethanolamide (PEA) compared to ibuprofen for reducing pain severity and duration of headaches in healthy participants aged 18 years and older.
Headache
RDC Global Pty Ltd80 enrolled1 locationACTRN12618000294257
Completed
Phase 4
Effect of High Flow Tracheostomy Device for weaning from Mechanical Ventilation
Mechanical VentilationTracheostomy
The Prince Charles Hospital20 enrolled1 locationACTRN12616001145493
Completed
Phase 3Phase 4
The Effect of Intranasal Dexmedetomidine Premedication on the Minimum Alveolar Concentration of Sevoflurane for tracheal intubation in children
inhalation induction of anesthesia and tracheal intubation in children
Yusheng Yao90 enrolled1 locationACTRN12613000679785
Completed
Phase 4
Controlled comparison between siccoral spraying, stomatovis gargle or strefen tablets to reduce postoperative sore throat in patients undergoing elective genitourinary surgery under general anesthesia with orotracheal intubation
We are studying postoperative sore throat(POST) after general anesthesia with orotracheal intubation.
Gozde Bumin Aydin320 enrolled1 locationACTRN12613000477729
Completed
Phase 4
Effect of Rocuronium and Sugammadex on Myalgia and Headache After Electro-Convulsive Therapy
Headache after electroconvulsive therapy (ECT)Myalgia after electroconvulsive therapy (ECT)
Gaziantep University48 enrolled1 locationACTRN12613000054718
Completed
Phase 4
Evaluation of performance of cuffed and uncuffed endotracheal tubes in a paediatric population: A randomised controlled trial.
We hypothesise that the rate of respiratory complications will be similar between the groups receiving either cuffed or uncuffed endotracheal tubes.We hypothesize that there will be a higher rate of endotracheal tube leak in uncuffed compared with cuffed tubes, and that the rate of sore throat will be higher in the uncuffed group.We furthermore hypothesise that the loss in lung volume following a standardized recruitment maneouver will be greater in the children intubated with uncuffed ETTs as compared with cuffed ETTs.
Princess Margaret Hospital for Children104 enrolled1 locationACTRN12612000045819
Terminated
Phase 4
Impact of topical lignocaine on the incidence of perioperative respiratory complications in children undergoing laryngo-tracheo-bronchoscopies – a double blind randomised controlled pilot study
Respiratory complications following topical lignocaine onto the vocal cords for laryngotracheobronchoscopies
Prof Britta Regli-von Ungern-Sternberg200 enrolled1 locationACTRN12610000235000
Recruiting
Phase 3Phase 4
Exogenous Melatonin to Improve Sleep in Critically Ill Patients
Poor sleep in tracheostomised ICU patients.
The Alfred60 enrolled1 locationACTRN12610000008022
Completed
Phase 4
A comparison of oral prednisolone and oral dexamethasone in children with croup: a prospective, randomised, double blinded multicentre trial
Croup (laryngotracheitis, laryngotracheobronchitis)
Dr Colin Parker1,400 enrolled1 locationACTRN12609000290291
Completed
Phase 3Phase 4
Comparison between single dose oral prednisolone and oral dexamethasone in the treatment of croup: a randomised, double-blind clinical trial.
Croup (laryngotracheobronchitis)
Mater Childrens' Hospital Department of Paediatric Emergency Medicine100 enrolled1 locationACTRN12605000447651