ACL Tear Clinical Trials

9 recruitingLast updated: May 13, 2026

There are 9 actively recruiting acl tear clinical trials across 4 countries. Studies span Not Applicable, Phase 2. Top locations include Cleveland, Ohio, United States, Boston, Massachusetts, United States, Centennial, Colorado, United States. Updated daily from ClinicalTrials.gov.


ACL Tear Trials at a Glance

9 actively recruiting trials for acl tear are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Cleveland, Boston, and Centennial. Lead sponsors running acl tear studies include Brigham and Women's Hospital, CONMED Corporation, and Ann & Robert H Lurie Children's Hospital of Chicago.

Browse acl tear trials by phase

Treatments under study

About ACL Tear Clinical Trials

Looking for clinical trials for ACL Tear? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new ACL Tear trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about ACL Tear clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting

Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?

ACL InjuryACL TearACL - Anterior Cruciate Ligament Rupture
University of Liverpool55 enrolled1 locationNCT06235736
Recruiting
Not Applicable

Quadriceps Strengthening ACL Reconstruction

ACL Tear
Stanford University40 enrolled1 locationNCT07015541
Recruiting

BioBrace® Augmentation in Anterior Cruciate Ligament Reconstruction Procedures

ACL Tears
CONMED Corporation500 enrolled1 locationNCT06948591
Recruiting

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Musculoskeletal DiseasesOsteoarthritisJoint Diseases+3 more
Xiaojuan Li88 enrolled1 locationNCT04536103
Recruiting
Not Applicable

Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation

ACL Tear
University of Colorado, Denver78 enrolled1 locationNCT05735236
Recruiting
Phase 2

Preventing Injured Knees From osteoArthritis: Severity Outcomes

Osteoarthritis, KneePost-traumatic OsteoarthritisACL Tear
Brigham and Women's Hospital512 enrolled9 locationsNCT06096259
Recruiting
Not Applicable

The Pediatric ALL Evaluation and Trial

ACL InjuryACL Tear
Ann & Robert H Lurie Children's Hospital of Chicago240 enrolled1 locationNCT04825587
Recruiting

Exploring Prolonged AMR in ACL Reconstructed Patients

Anterior cruciate ligament ruptureAnterior Cruciate Ligament InjuriesACL Injury+6 more
University Ghent190 enrolled1 locationNCT06430775
Recruiting
Not Applicable

Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction Surgery

Pain, PostoperativeACL Tear
Hospital Clinic of Barcelona40 enrolled1 locationNCT06486246