Phase 1 Acne Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Acne
Sanofi Pasteur, a Sanofi Company800 enrolled93 locationsNCT06316297
Recruiting
Phase 1
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
Acne
Sagimet Biosciences Inc.128 enrolled2 locationsNCT06989840
Recruiting
Phase 1Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Acne
Sanofi Pasteur, a Sanofi Company120 enrolled4 locationsNCT07013747
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 40 mg isotretinoin capsule against the innovator 1 x 40 mg isotretinoin capsule conducted under fed conditions in healthy male volunteers.
Isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corp Ltd40 enrolled1 locationACTRN12619000154101
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 40 mg isotretinoin capsule against the innovator 1 x 40 mg isotretinoin capsule conducted under fasting conditions in healthy male volunteers.
Isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corp Ltd38 enrolled1 locationACTRN12618001804279
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 30 mg isotretinoin capsule against the innovator 1 x 30 mg isotretinoin capsule conducted under fed conditions in healthy male volunteers.
Isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corporation Limited40 enrolled1 locationACTRN12618000935235
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 30 mg isotretinoin capsule against the innovator 1 x 30 mg isotretinoin capsules conducted under fasting conditions in healthy male volunteers.
Isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corp Ltd36 enrolled1 locationACTRN12617001407381
Completed
Phase 1
Study of BTX 1503 Solution in Patients with Acne Vulgaris
Acne
Botanix Pharmaceuticals Ltd16 enrolled4 locationsACTRN12617001127392
Completed
Phase 1
A safety study of BTX1503 Solution in Healthy Volunteers
Acne
Botanix Pharmaceuticals Ltd24 enrolled1 locationACTRN12617000642381
Completed
Phase 1
Comparative assessment in healthy male volunteers under fasting conditions of the absorption and pharmacokinetics of a test formulation of isotretinoin capsule against an innovator isotretinoin capsule in a pilot study
Acne
Zenith Technology Corporation Limited16 enrolled1 locationACTRN12616000663459
Completed
Phase 1
Comparative assessment in healthy male volunteers under fasting conditions of the absorption and pharmacokinetics of 3 generic formulations of isotretinoin capsules against the innovator isotretinoin capsule in a pilot study
Pilot study conducted in healthy volunteers comparing four formulations of isotretinoin with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corp Ltd16 enrolled1 locationACTRN12615001083583
Completed
Phase 1
Comparative assessment of the absorption of 3 generic formulations of isotretinoin capsules against the innovator isotretinoin capsule in a pilot study conducted under fasting conditions in healthy male volunteers
Pilot study conducted in healthy volunteers comparing four formulations of isotretinoin with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, isotretinoin is a medicine that is used to treat severe forms of acne.
Zenith Technology Corp Ltd16 enrolled1 locationACTRN12615000569505
Completed
Phase 1
A Phase 1 Single-Center, Randomized, Placebo-Controlled, Double-Blind Pilot Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Candidate Topical Antimicrobial (NEO101) in the Reduction of Propionibacterium acnes among Healthy Young Adult Men
Propionibacterium acnes amongst healthy volunteers
Neosil, Inc.30 enrolled1 locationACTRN12606000424505