Phase 2 Acne Clinical Trials

12 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 112 of 12 trials

Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne
Sanofi Pasteur, a Sanofi Company800 enrolled93 locationsNCT06316297
Recruiting
Phase 2

Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne

Acne
Shenzhen People's Hospital196 enrolled1 locationNCT07366229
Recruiting
Phase 2

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors

ParonychiaAcneiform Eruption Due to ChemicalXerosis Cutis
Hoth Therapeutics, Inc.152 enrolled12 locationsNCT05639933
Not Yet Recruiting
Phase 2Phase 3

Comparing the therapeutic efficacy of oral low dose versus pulsed dose oral isotretinoin in moderate acne vulgaris patients presenting in PNS Shifa Hospital, Karachi

Acne vulgaris
PNS Shifa90 enrolled1 locationACTRN12625000983404
Recruiting
Phase 1Phase 2

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

Acne
Sanofi Pasteur, a Sanofi Company120 enrolled4 locationsNCT07013747
Recruiting
Phase 2

A Phase 2, Proof-of-concept, Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AT-5214 in Subjects with Moderate to Severe Facial Acne Vulgaris

Acne vulgaris
Atacama Therapeutics Australia, Pty Ltd.100 enrolled2 locationsACTRN12624000746538
Recruiting
Phase 2

Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

AcnePhotodynamic Therapy
Xiyuan Hospital of China Academy of Chinese Medical Sciences46 enrolled1 locationNCT06311890
Completed
Phase 2

A Randomized, Double-Blind, Vehicle-Controlled Study to Evaluate the Safety and Efficacy of BTX 1503 in Patients with Moderate to Severe Acne Vulgaris

Acne vulgaris
Botanix Pharmaceuticals Ltd360 enrolled12 locationsACTRN12618001047280
Completed
Phase 2

A single-blind randomised controlled trial of topical Kanuka honey for the treatment of Acne

Acne
Honeylab Ltd138 enrolled1 locationACTRN12614000003673
Completed
Phase 2

Comparison of the efficacy, safety and tolerability of topically applied tretinoin formulated with TPM, a lead commercially available tretinoin cream and a vehicle (placebo) in the treatment of mild to moderate acne vulgaris

Treatment of acne vulgaris
Phosphagenics45 enrolled1 locationACTRN12613000756729
Completed
Phase 2Phase 3

Isotretinoin 5mg capsules (once daily) in the treatment of persistent low grade adult acne.

Persistent low grade adult acne.
Douglas Pharmaceuticals Ltd60 enrolled1 locationACTRN12612000062820
Completed
Phase 2

Phase 2, 'Proof of Principle', Placebo Controlled, Randomised, Parallel Group Pilot Study of the Effect of a New Combined Acne Treatment in Patients with Mild to Moderate Acne.

Mild to Moderate Acne vulgaris
LifeSource Group Holdings Pty Ltd20 enrolled1 locationACTRN12607000140459