Early Phase 1 Action Clinical Trials

11 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 111 of 11 trials

Recruiting
Early Phase 1

Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia

Third Molars Extraction
Henrique Tedesco15 enrolled1 locationNCT07108465
Recruiting
Early Phase 1

SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

Heart Failure With Preserved Ejection FractionType2 Diabetes
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT05057806
Recruiting
Early Phase 1

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-drug Interaction
Indiana University60 enrolled1 locationNCT05789173
Recruiting
Early Phase 1

Ketones, SGLT2, HFrEF

Heart Failure With Reduced Ejection FractionType2diabetes
The University of Texas Health Science Center at San Antonio71 enrolled1 locationNCT06229678
Recruiting
Early Phase 1

Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

Type 2 DiabetesHeart Failure, Reduced Ejection Fraction
The University of Texas Health Science Center at San Antonio10 enrolled1 locationNCT06108076
Recruiting
Early Phase 1

Intradermal Influenza Vaccination

Vaccine Reaction
Yale University249 enrolled1 locationNCT06067555
Recruiting
Early Phase 1

A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction

Acute Post Operative PainThird Molar Extraction Surgery
Arcato Laboratories, Inc.30 enrolled1 locationNCT06864884
Recruiting
Early Phase 1

Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints

Herbal Interaction
Washington State University16 enrolled1 locationNCT05846451
Recruiting
Early Phase 1

Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach

Interaction
Washington State University16 enrolled1 locationNCT06693960
Recruiting
Early Phase 1

Effects of a Hemp Product on the Pharmacokinetics and Pharmacodynamics of Clopidogrel

Interaction
Washington State University24 enrolled1 locationNCT06692933
Recruiting
Early Phase 1

Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac

Interaction
Washington State University30 enrolled1 locationNCT06053411