Phase 2 Action Clinical Trials

53 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 53 trials

Recruiting
Phase 2

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

NeoplasmsVomitingNausea+1 more
Eli Lilly and Company204 enrolled67 locationsNCT07169851
Recruiting
Phase 2

Lumacaftor Yields Reversal of Impaired Cerebral Blood Flow in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Qanatpharma AG60 enrolled2 locationsNCT07695090
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 2

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

Heart Failure With Preserved Ejection Fraction
Massachusetts General Hospital48 enrolled1 locationNCT07202000
Recruiting
Phase 2

A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure

Heart Failure With Preserved Ejection Fraction
Mayo Clinic35 enrolled1 locationNCT07083011
Recruiting
Phase 2Phase 3

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure

ObesityWeight LossHeart Failure With Reduced Ejection Fraction+1 more
Jens D Hove, MD,PHD100 enrolled1 locationNCT06423599
Recruiting
Phase 2Phase 3

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 2Phase 3

Virtual Menstrual Pain Approaches in Females

Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Phase 2

Matching Perfusion and Metabolic Activity in HFpEF

Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT04913805
Recruiting
Phase 2

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics60 enrolled25 locationsNCT06793371
Recruiting
Phase 2

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

antibiotic allergyDrug hypersensitivityCephalosporin Allergy+4 more
Massachusetts General Hospital300 enrolled6 locationsNCT06406114
Recruiting
Phase 1Phase 2

Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions

Healthy VolunteerVancomycinHypersensitivity Reactions
Johns Hopkins University25 enrolled1 locationNCT07605806
Recruiting
Phase 1Phase 2

Opioid Drug Interaction Study

Drug Kineticsdrug interactions
Shanna Babalonis, PhD25 enrolled1 locationNCT06757140
Recruiting
Phase 2

A Phase II Clinical Trial of HRS-1893 in the Treatment of Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction
Shandong Suncadia Medicine Co., Ltd.48 enrolled1 locationNCT07269717
Recruiting
Phase 2

CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation

HFpEF - Heart Failure With Preserved Ejection FractionFontan CirculationSingle Ventricle Heart Disease
Mayo Clinic27 enrolled1 locationNCT06762964
Recruiting
Phase 1Phase 2

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Quality of LifeDepression, AnxietyStress Reaction+1 more
Children's Hospital Los Angeles66 enrolled1 locationNCT05685368
Recruiting
Phase 2

Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction

Coronary Artery DiseaseHeart Failure With Preserved Ejection Fraction (HFpEF)
King's College London350 enrolled1 locationNCT07560436
Recruiting
Phase 2

SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT05138575
Recruiting
Phase 2

BXCL501 After Stress to Increase Recovery Success

Post Traumatic Stress DisorderAcute Stress DisorderAcute Stress Reaction
University of North Carolina, Chapel Hill100 enrolled3 locationsNCT06943404
Recruiting
Phase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786