Early Phase 1 Acute Myeloid Leukemia Clinical Trials

13 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 113 of 13 trials

Recruiting
Early Phase 1

Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy

Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia
City of Hope Medical Center74 enrolled1 locationNCT03422731
Recruiting
Early Phase 1

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

Acute Myeloid LeukemiaPediatric AML
Joanna Yi36 enrolled1 locationNCT07059975
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Chronic Myeloid LeukemiaHodgkin LymphomaNon-Hodgkin Lymphoma+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

Donor Derived CD117 CAR-T Cells in the Treatment of R/R Acute Myeloid Leukemia

Acute Myeloid Leukemia
Zhejiang University50 enrolled1 locationNCT07144020
Recruiting
Early Phase 1

XP-005 Personalized Vaccine Alone or in Combination With Toripalimab for the Prevention of Relapse After Remission in Acute Myeloid Leukemia

Acute Myeloid Leukemia
Shanghai Jiao Tong University School of Medicine60 enrolled1 locationNCT06980155
Recruiting
Early Phase 1

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Acute Myeloid LeukemiaMyelodysplastic SyndromesChronic Myelomonocytic Leukemia+4 more
Omar Aljitawi24 enrolled1 locationNCT03964506
Recruiting
Early Phase 1

Off-the-shelf CD123 CAR-NK for R/R AML

Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Peking University People's Hospital12 enrolled1 locationNCT06201247
Recruiting
Early Phase 1

Evaluation of the Safety and Efficacy of Human CI-135 (FLT3) Targeted CAR-T Cells Injection for Subjects with Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)
Hrain Biotechnology Co., Ltd.7 enrolled1 locationNCT06760260
Recruiting
Early Phase 1

A Clinical Study to Explore the Safety and Efficacy of CD33 CAR-T Cell in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia
Zhejiang University27 enrolled1 locationNCT06762132
Recruiting
Early Phase 1

EX02 CAR-T Cells for Relapsed and Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)CAR-T
Zhimin Zhai9 enrolled1 locationNCT06642025
Recruiting
Early Phase 1

Safety and Efficacy of NK520 to Treat Pediatric Relapsed/Refractory Acute Myeloid Leukemia

Relapsed/Refractory Acute Myeloid Leukemia
Base Therapeutics (Shanghai) Co., Ltd.9 enrolled1 locationNCT06541405
Recruiting
Early Phase 1

Safety and Efficacy of NK520 to Treat Relapsed/Refractory Acute Myeloid Leukemia

Relapsed/Refractory Acute Myeloid Leukemia
Base Therapeutics (Shanghai) Co., Ltd.9 enrolled1 locationNCT06541444
Recruiting
Early Phase 1

CD 70 CAR T for Patients With CD70 Positive Malignant Hematologic Diseases

Acute Myeloid LeukemiaMultiple MyelomaNon-Hodgkin's Lymphoma
Zhejiang University108 enrolled1 locationNCT04662294