Phase 3 Acute Clinical Trials
269 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 269 trials
Recruiting
Phase 2Phase 3
L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML
Acute Myeloid Leukaemia (AML)
Moleculin Biotech, Inc.312 enrolled25 locationsNCT06788756
Recruiting
Phase 3
Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
Acute promyelocytic leukaemiaAcute Promyelocytic LeukemiaAcute Promyelocytic Leukemia With PML-RARA+2 more
Quetzal Therapeutics150 enrolled7 locationsNCT07504458
Recruiting
Phase 3
A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia
B-cell Acute Lymphoblastic Leukemia
Memorial Sloan Kettering Cancer Center130 enrolled5 locationsNCT07223021
Recruiting
Phase 3
rhTNK-tPA for Acute Ischemic Stroke Under Simplified Imaging in the Extended Time Window
Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University750 enrolled1 locationNCT07606807
Recruiting
Phase 3
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
Adult Acute Myeloid Leukemia
Priothera SAS366 enrolled108 locationsNCT05429632
Recruiting
Phase 3
Single Bolus Non-immunogenic Staphylokinase in Patients With Acute Ischemic Stroke Within 4.5-24 Hours of Symptom Onset
Ischemic Stroke, Acute
Supergene, LLC990 enrolled15 locationsNCT07324837
Recruiting
Phase 3
Study of Out of Specification for Tisagenlecleucel
Diffuse Large B Cell LymphomaB-cell Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals200 enrolled53 locationsNCT04094311
Recruiting
Phase 3
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Acute Ischemic StrokeCerebral Stroke
Pharmazz, Inc.514 enrolled55 locationsNCT05691244
Recruiting
Phase 3
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
Acute Myeloid LeukemiaRelapse/Recurrence
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS339 enrolled47 locationsNCT06713837
Recruiting
Phase 3
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
Acute Coronary SyndromeTuberculosisPulmonary Hypertension (Diagnosis)
National University Hospital, Singapore150 enrolled6 locationsNCT05473520
Recruiting
Phase 3
A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well
Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled242 locationsNCT07361302
Recruiting
Phase 3
Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks
Acute Hereditary Angio Edema
Octapharma124 enrolled21 locationsNCT06361537
Recruiting
Phase 3
Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion
Acute Cerebrovascular AccidentBasilar Artery OcclusionStroke Due to Basilar Artery Occlusion
The First Affiliated Hospital of University of Science and Technology of China338 enrolled1 locationNCT05827042
Recruiting
Phase 3
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Acute Treatment of Migraine
Pfizer600 enrolled126 locationsNCT04743141
Recruiting
Phase 3
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Leukemia, Myeloid, Acute
Janssen Research & Development, LLC600 enrolled250 locationsNCT06852222
Recruiting
Phase 2Phase 3
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis
PericarditisRecurrent PericarditisPericarditis Acute
Kiniksa Pharmaceuticals International, plc165 enrolled58 locationsNCT07010159
Recruiting
Phase 2Phase 3
Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeSedation Complication
Guy's and St Thomas' NHS Foundation Trust20 enrolled1 locationNCT06014138
Recruiting
Phase 2Phase 3
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC340 enrolled3 locationsNCT07570173
Recruiting
Phase 3
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Acute Myeloid Leukemia (AML)
Kura Oncology, Inc.1,300 enrolled71 locationsNCT07007312
Recruiting
Phase 3
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia
Alliance for Clinical Trials in Oncology310 enrolled460 locationsNCT03150693