Phase 2 Age-Related Macular Degeneration Clinical Trials
27 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 27 trials
Recruiting
Phase 2
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration
Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
Adverum Biotechnologies, Inc.15 enrolled4 locationsNCT07630649
Recruiting
Phase 1Phase 2
Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration
Neovascular (Wet) Age-related Macular Degeneration
Eyconis INC.30 enrolled5 locationsNCT07587515
Recruiting
Phase 2Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Age-Related Macular DegenerationMacular DegenerationChoroidal Neovascularization+1 more
EyeBiotech Ltd.960 enrolled30 locationsNCT07440225
Recruiting
Phase 2Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
Age-Related Macular DegenerationMacular DegenerationChoroidal Neovascularization+1 more
EyeBiotech Ltd.960 enrolled9 locationsNCT07496567
Recruiting
Phase 1Phase 2
A Study of PRL3-zumab in Neovascular Age-related Macular Degeneration (nAMD)
Neovascular Age-related Macular Degeneration
Intra-IMMUSG Pte Ltd15 enrolled1 locationNCT07547228
Recruiting
Phase 2
A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)
Geographic AtrophyDry Age-Related Macular Degeneration
Regenerative Patch Technologies, LLC24 enrolled5 locationsNCT06557460
Recruiting
Phase 1Phase 2
Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Geographic AtrophyAge-Related Macular Degeneration
AbbVie66 enrolled4 locationsNCT07160179
Recruiting
Phase 1Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
Neovascular (Wet) Age-related Macular Degeneration
4D Molecular Therapeutics215 enrolled25 locationsNCT05197270
Recruiting
Phase 1Phase 2
Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration
Geographic AtrophyDry Age-Related Macular Degeneration
National Eye Institute (NEI)20 enrolled2 locationsNCT04339764
Recruiting
Phase 2
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD
Age-Related Macular Degeneration
Massachusetts Eye and Ear Infirmary21 enrolled1 locationNCT04735263
Recruiting
Phase 1Phase 2
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD
Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)
Bionic Sight LLC40 enrolled1 locationNCT07158775
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD
Neovascular Age-related Macular Degeneration
Innovent Biologics Technology Limited (Shanghai R&D Center)800 enrolled1 locationNCT07275840
Recruiting
Phase 1Phase 2
Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Neovascular Age-Related Macular Degeneration (nAMD)
Alcon Research140 enrolled42 locationsNCT05769153
Recruiting
Phase 1Phase 2
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration
Neovascular Age-related Macular Degeneration
Sanofi66 enrolled18 locationsNCT06660667
Recruiting
Phase 2
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
Neovascular Age-Related Macular Degeneration (NVAMD)Branch Retinal Vein Occlusion (BRVO)
EyeBiotech Ltd.160 enrolled49 locationsNCT07205887
Recruiting
Phase 1Phase 2
Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration
Geographic AtrophyAge-Related Macular DegenerationNon-neovascular AMD
Perceive Biotherapeutics, Inc.60 enrolled11 locationsNCT06087458
Recruiting
Phase 1Phase 2
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Dry Age-Related Macular Degeneration
Luxa Biotechnology, LLC18 enrolled3 locationsNCT04627428
Recruiting
Phase 1Phase 2
Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies
Retinitis pigmentosa (RP)Age-Related Macular DegenerationDiabetic Retinopathy
Ace Cells Lab Limited100 enrolled2 locationsNCT06787482
Recruiting
Phase 1Phase 2
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Neovascular Age-related Macular Degeneration
Skyline Therapeutics (US) Inc.68 enrolled9 locationsNCT05986864
Recruiting
Phase 1Phase 2
Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)
Age-Related Macular Degeneration
Chengdu Origen Biotechnology Co., Ltd.44 enrolled1 locationNCT06458595