Phase 3 AIN Clinical Trials

299 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 299 trials

Recruiting
Phase 3

Mechanisms of Stimulation for Pain Alleviation

Chronic Neuropathic PainPeripheral Nerve StimulationChronic Neuropathic Pain (Below the Shoulders)
Stanford University148 enrolled2 locationsNCT06741579
Recruiting
Phase 3

RADA16 for Adult Tonsillectomy

Postoperative Pain
Rutgers, The State University of New Jersey134 enrolled2 locationsNCT07060495
Recruiting
Phase 3

BOTOX® vs. XEOMIN® for Chronic Migraine

Chronic Migraine
Naval Medical Center Camp Lejeune128 enrolled1 locationNCT05598723
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

Migraine
Kallyope Inc.1,800 enrolled115 locationsNCT07645924
Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 3

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

Non-small Cell Lung CancerBrain Tumor
InSightec30 enrolled13 locationsNCT05317858
Recruiting
Phase 3

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled21 locationsNCT07226258
Recruiting
Phase 3

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

ObesityWeight Gain
Eli Lilly and Company300 enrolled72 locationsNCT06439277
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathic pain
Vertex Pharmaceuticals Incorporated734 enrolled75 locationsNCT07231419
Recruiting
Phase 3

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Complex Regional Pain Syndrome Type I
Ambros Therapeutics, Inc.270 enrolled19 locationsNCT07210515
Recruiting
Phase 3

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Episodic Migraine
AbbVie450 enrolled98 locationsNCT05711394
Recruiting
Phase 3

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine
AbbVie420 enrolled64 locationsNCT06810505
Recruiting
Phase 3

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine

Episodic Migraine
H. Lundbeck A/S315 enrolled65 locationsNCT05897320
Recruiting
Phase 3

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

Chronic Migraine in Children
H. Lundbeck A/S285 enrolled84 locationsNCT04965675
Recruiting
Phase 3

Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia

Neuropathic PainDiabetic NeuropathyNeuralgia, Postherpetic
Brainfarma Industria Química e Farmacêutica S/A348 enrolled15 locationsNCT07712913
Recruiting
Phase 3

Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

Traumatic Brain InjuryMilitary Operations
University of South Florida420 enrolled1 locationNCT06581003
Recruiting
Phase 2Phase 3

Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Abdominal Surgery

Postoperative Pain
Shanghai Huilun Pharmaceutical Co., Ltd.330 enrolled1 locationNCT07709598
Recruiting
Phase 3

R.E.C.K vs Exparel in Robotic Nephrectomy

Pain ManagementRenal CarcinomaNephrectomy / Methods
Wake Forest University Health Sciences170 enrolled1 locationNCT07092566
Recruiting
Phase 3

Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease

Vaso-Occlusive Pain Episode in Sickle Cell Disease
Nantes University Hospital104 enrolled11 locationsNCT07274254
Recruiting
Phase 3

Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of Dysmenorrhea

Primary DysmenorrheaChronic pelvic pain
Nantes University Hospital222 enrolled8 locationsNCT06995287