Phase 3 Alcohol Clinical Trials
32 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 32 trials
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.762 enrolled296 locationsNCT06419374
Recruiting
Phase 3
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
89bio, Inc.1,350 enrolled342 locationsNCT06318169
Recruiting
Phase 2Phase 3
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Alcohol MisuseHomeless
University of Oklahoma600 enrolled1 locationNCT06821295
Recruiting
Phase 3
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
MASH - Metabolic Dysfunction-Associated SteatohepatitisNASH - Nonalcoholic Steatohepatitis
Akero Therapeutics, Inc2,150 enrolled318 locationsNCT06528314
Recruiting
Phase 3
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled119 locationsNCT07219966
Recruiting
Phase 3
A Study of Brenipatide in Participants With Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled114 locationsNCT07219953
Recruiting
Phase 3
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
Non-Alcoholic Fatty Liver Disease
GlaxoSmithKline1,200 enrolled49 locationsNCT07221227
Recruiting
Phase 3
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
Non-Alcoholic Fatty Liver Disease
GlaxoSmithKline1,250 enrolled43 locationsNCT07221188
Recruiting
Phase 2Phase 3
Effect of Nutritional Ketosis on Alcohol Metabolism
Magnetic Resonance ImagingAlcohol DrinkingKetogenic Dieting+2 more
University of Pennsylvania20 enrolled1 locationNCT06065657
Recruiting
Phase 2Phase 3
Effects of Ketone Supplement and Alcohol on Brain Metabolism
MRIKetosisAlcohol Drinking
University of Pennsylvania60 enrolled1 locationNCT06815237
Recruiting
Phase 2Phase 3
Ketone Ester Intervention in Alcohol Use Disorder
Alcohol DrinkingAlcohol Use Disorder
University of Pennsylvania20 enrolled1 locationNCT04616781
Recruiting
Phase 3
Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease
Tobacco SmokingAlcohol-Related Disorders
VA Office of Research and Development270 enrolled1 locationNCT07039175
Recruiting
Phase 3
Using Hydroxychloroquine (HCQ) to Treat Steatohepatitis
Steatohepatitis, Nonalcoholic
National Taiwan University Hospital210 enrolled1 locationNCT07265297
Recruiting
Phase 2Phase 3
Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder
alcohol withdrawalKetosisAlcohol Use Disorder
University of Pennsylvania30 enrolled1 locationNCT06559995
Recruiting
Phase 3
Estrogen Administration for the Treatment of NASH in Postmenopausal Women
NASH - Nonalcoholic Steatohepatitis
Massachusetts General Hospital60 enrolled1 locationNCT04833140
Recruiting
Phase 3
Electronic Harm Reduction Treatment for Alcohol
Alcohol Use DisorderHarm ReductionHousing First (eg. Permanent Supportive Housing)
University of Washington160 enrolled1 locationNCT06702007
Recruiting
Phase 3
Emergency Department-Initiated Medications for Alcohol Use Disorder
Alcohol Use Disorder
Yale University240 enrolled1 locationNCT05827159
Recruiting
Phase 3
Short Course Steroids in Alcohol Associated Hepatitis
Alcoholic Hepatitis
Asian Institute of Gastroenterology, India146 enrolled2 locationsNCT06919458
Recruiting
Phase 2Phase 3
Efficacy of Simvastatin in Alcoholic Liver Fibrosis
Liver FibrosisAlcohol Abuse
Anna Cruceta90 enrolled1 locationNCT04971577
Recruiting
Phase 2Phase 3
Alcohol Use Disorder and Cannabidiol
Alcohol Use Disorder
University of Colorado, Denver180 enrolled1 locationNCT05613608