Phase 2 Alcohol Clinical Trials
101 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 101 trials
Recruiting
Phase 2
Semaglutide Therapy for Alcohol Reduction (STAR)
Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 2
Guanfacine for Alcohol Use Disorder (AUD)
Alcohol Use Disorder
Indiana University200 enrolled2 locationsNCT06629259
Recruiting
Phase 1Phase 2
Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Phase 2
Evaluating the Safety and Efficacy of Carbocisteine in the Treatment of Nonalcoholic Fatty Liver Disease Patients
Non-Alcoholic Fatty Liver Disease
Tanta University46 enrolled1 locationNCT06863376
Recruiting
Phase 2
Human Laboratory Study of Apremilast for Alcohol Use Disorder
Alcohol Use DisorderAlcohol Misuse
National Institute on Alcohol Abuse and Alcoholism (NIAAA)100 enrolled3 locationsNCT07325266
Recruiting
Phase 2
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 2
Brexpiprazole in Alcohol Use Disorder
Alcohol Use Disorder
University of Colorado, Denver250 enrolled1 locationNCT04066192
Recruiting
Phase 2Phase 3
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Alcohol MisuseHomeless
University of Oklahoma600 enrolled1 locationNCT06821295
Recruiting
Phase 2
Motivation for IV Alcohol Self-Administration in Humans
Alcohol Use Disorder
University of California, Los Angeles210 enrolled1 locationNCT06494891
Recruiting
Phase 2
Ketamine Alcohol (in Treatment-Resistant Depression)
Magnetic Resonance ImagingAlcoholismMajor Depression
Mark Niciu60 enrolled1 locationNCT02122562
Recruiting
Phase 1Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 2
LSD Treatment for Persons With Alcohol Use Disorder
Alcohol Use Disorder (AUD)
Felix Mueller128 enrolled2 locationsNCT05474989
Recruiting
Phase 2
GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV
Cardiovascular Disease PreventionSmoking, CigaretteHIV+1 more
Vanderbilt University Medical Center200 enrolled1 locationNCT07221214
Recruiting
Phase 2
Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD
Alcohol Use DisorderPosttraumatic Stress Disorder
Texas A&M University200 enrolled2 locationsNCT05959434
Recruiting
Phase 2
Tirzepatide in MetALD
Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2
Cannabidiol and Alcohol Use Disorder Phenotypes
Alcohol Use Disorder
University of Colorado, Denver150 enrolled1 locationNCT07279558
Recruiting
Phase 2
A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease
Liver Diseases, Alcoholic
GlaxoSmithKline393 enrolled131 locationsNCT06613698
Recruiting
Phase 1Phase 2
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
Alcohol Use Disorder
Clearmind Medicine Inc.84 enrolled4 locationsNCT05913752
Recruiting
Phase 2
SAMe Trial for Patients With Alcoholic Cirrhosis
Alcoholic Cirrhosis
Indiana University196 enrolled2 locationsNCT04250259
Recruiting
Phase 2Phase 3
Effects of Ketone Supplement and Alcohol on Brain Metabolism
MRIKetosisAlcohol Drinking
University of Pennsylvania60 enrolled1 locationNCT06815237