Alcohol Clinical Trials

594 recruitingLast updated: July 25, 2026

There are 594 actively recruiting alcohol clinical trials across 55 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, New Haven, Connecticut, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Alcohol Trials at a Glance

594 actively recruiting trials for alcohol are listed on ClinicalTrialsFinder across 6 cities in 55 countries. The largest study group is Not Applicable with 290 trials, with the heaviest enrollment activity in New York, New Haven, and Baltimore. Lead sponsors running alcohol studies include Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA), and VA Office of Research and Development.

Treatments under study

About Alcohol Clinical Trials

Looking for clinical trials for Alcohol? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alcohol trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alcohol clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 594 trials

Recruiting
Phase 1

Environment and Alcohol: A Pilot Study

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting
Phase 1

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

Alcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)176 enrolled1 locationNCT07559500
Recruiting

Hepatic Lipid Metabolism-Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)25 enrolled1 locationNCT07191561
Recruiting

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

AlcoholismSubstance-Related Disorders
National Institute on Drug Abuse (NIDA)10,000 enrolled1 locationNCT06676059
Recruiting
Not Applicable

Role of Acetaldehyde in the Development of Oral Cancer

Fanconi AnemiaOral Cavity CarcinomaAlcohol-Related Carcinoma
Masonic Cancer Center, University of Minnesota170 enrolled1 locationNCT05973656
Recruiting
Phase 4

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)48 enrolled1 locationNCT06269627
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 1

Spironolactone in Alcohol Use Disorder (SAUD)

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)20 enrolled1 locationNCT05807139
Recruiting

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Substance Use DisorderAlcohol Use Disorder
National Institute on Drug Abuse (NIDA)10,000 enrolled1 locationNCT06552741
Recruiting
Not Applicable

Understanding Pathways to Wellness and Recovery in Detroit - Digital Recovery Support Services

Digital HealthAlcohol Use DisorderRecovery Outcomes
Brandeis University65 enrolled1 locationNCT07724275
Recruiting
Phase 3

A Study of Brenipatide in Participants With Alcohol Use Disorder

Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled117 locationsNCT07219953
Recruiting
Phase 3

Emergency Department-Initiated Medications for Alcohol Use Disorder

Alcohol Use Disorder
Yale University240 enrolled1 locationNCT05827159
Recruiting
Phase 3

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled120 locationsNCT07219966
Recruiting
Not Applicable

Alcohol and "Heat of the Moment" Sexual Decision Making

Alcohol DrinkingHIVSex, Unsafe
Boston University Charles River Campus354 enrolled1 locationNCT05729256
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting
Not Applicable

Alcohol & Men's Sexual Risk Behaviors

EmotionsAlcohol DrinkingSexual Behavior+1 more
Arizona State University320 enrolled1 locationNCT06158880
Recruiting
Phase 3

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

MASH - Metabolic Dysfunction-Associated SteatohepatitisNASH - Nonalcoholic Steatohepatitis
Akero Therapeutics, Inc2,150 enrolled323 locationsNCT06528314
Recruiting
Not Applicable

The Trans-Led Care Study

Substance AbuseSubstance AddictionSubstance Use Disorder (SUD)+2 more
Illinois Institute of Technology124 enrolled1 locationNCT06880705
Recruiting
Not Applicable

Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

Attention Deficit Hyperactivity DisorderFetal Alcohol Spectrum Disorders
University of California, Los Angeles30 enrolled1 locationNCT06847165