Alcohol Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Alcohol clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 480 trials

Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.762 enrolled291 locationsNCT06419374
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 1

Environment and Alcohol: A Pilot Study

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

AlcoholismSubstance-Related Disorders
National Institute on Drug Abuse (NIDA)10,000 enrolled1 locationNCT06676059
Recruiting
Not Applicable

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

Alcohol Use DisorderPosttraumatic Stress DisorderCouples
Medical University of South Carolina140 enrolled1 locationNCT05786157
Recruiting

Predicting Outcomes in Nonalcoholic Steatohepatitis With Advanced Fibrosis

Nonalcoholic Steatohepatitis
Virginia Commonwealth University240 enrolled2 locationsNCT05720663
Recruiting

NIAAA Natural History Protocol

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)7,500 enrolled1 locationNCT02231840
Recruiting
Phase 2

Cannabidiol and Alcohol Use Disorder Phenotypes

Alcohol Use Disorder
University of Colorado, Denver150 enrolled1 locationNCT07279558
Recruiting
Not Applicable

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Alcohol DrinkingAlcohol Use DisorderSubstance Use+2 more
Medical University of South Carolina86 enrolled1 locationNCT04998916
Recruiting
Phase 2

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

Liver Diseases, Alcoholic
GlaxoSmithKline393 enrolled131 locationsNCT06613698
Recruiting
Phase 1Phase 2

A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects

Alcohol Use Disorder
Clearmind Medicine Inc.84 enrolled4 locationsNCT05913752
Recruiting
Phase 2

SAMe Trial for Patients With Alcoholic Cirrhosis

Alcoholic Cirrhosis
Indiana University196 enrolled2 locationsNCT04250259
Recruiting

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

AlcoholismAlcohol DrinkingAlcohol Dependence+2 more
National Institute on Alcohol Abuse and Alcoholism (NIAAA)1,000 enrolled1 locationNCT02108080
Recruiting
Not Applicable

Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)

Alcohol Use Disorder
University of Michigan50 enrolled1 locationNCT07413458
Recruiting

A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic SteatohepatitisNonalcoholic Fatty Liver
Target PharmaSolutions, Inc.15,000 enrolled74 locationsNCT02815891
Recruiting
Not Applicable

The Trans-Led Care Study

Substance AbuseSubstance AddictionSubstance Use Disorder (SUD)+2 more
Illinois Institute of Technology124 enrolled1 locationNCT06880705
Recruiting
Phase 2Phase 3

Effect of Nutritional Ketosis on Alcohol Metabolism

Magnetic Resonance ImagingAlcohol DrinkingKetogenic Dieting+2 more
University of Pennsylvania20 enrolled1 locationNCT06065657
Recruiting
Phase 2Phase 3

Effects of Ketone Supplement and Alcohol on Brain Metabolism

MRIKetosisAlcohol Drinking
University of Pennsylvania60 enrolled1 locationNCT06815237
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting
Not Applicable

Deep Brain Stimulation to Understand and Treat Addiction

Alcohol Use Disorder
University of Cambridge9 enrolled2 locationsNCT07341230