Phase 2 Alzheimer Disease Clinical Trials
52 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 52 trials
Recruiting
Phase 2
Sleep Trial to Prevent Alzheimer's Disease
SleepAlzheimer Disease
Washington University School of Medicine200 enrolled1 locationNCT04629547
Recruiting
Phase 2
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Massachusetts General Hospital40 enrolled1 locationNCT07236190
Recruiting
Phase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Alzheimer DiseaseAgitation
Celgene120 enrolled53 locationsNCT06808984
Recruiting
Phase 2
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Alzheimer DiseaseAlzheimer Disease Due to P. Gingivalis
Lighthouse Pharmaceuticals, Inc.300 enrolled40 locationsNCT06847321
Recruiting
Phase 1Phase 2
Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease
Alzheimer DiseaseAlzheimer Disease, Early Onset
Arrowhead Pharmaceuticals112 enrolled3 locationsNCT07221344
Recruiting
Phase 2
Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.
Alzheimer DiseaseAgitation in Dementia
Bernard (Barry) Baumel8 enrolled1 locationNCT06781333
Recruiting
Phase 2
Clinical Trial on Agitation in Alzheimer's Dementia
Alzheimer DiseaseAggressionAgitation,Psychomotor+2 more
IGC Pharma, LLC164 enrolled31 locationsNCT05543681
Recruiting
Phase 2
Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition
Alzheimer DiseaseDown SyndromeDown Syndrome, Partial Trisomy 21
Vanderbilt University Medical Center30 enrolled1 locationNCT05231798
Recruiting
Phase 1Phase 2
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
Moderate Alzheimer Disease
NKGen Biotech, Inc.36 enrolled8 locationsNCT06189963
Recruiting
Phase 2
DORA and LP in Alzheimer's Disease Biomarkers
Alzheimer Disease
Washington University School of Medicine201 enrolled1 locationNCT06274528
Recruiting
Phase 2
Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
Alzheimer Disease
University of Colorado, Denver42 enrolled1 locationNCT04902703
Recruiting
Phase 2
Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD)
Alzheimer DiseaseCognitive Decline, Mild
Helse Stavanger HF200 enrolled6 locationsNCT06362707
Recruiting
Phase 1Phase 2
A Study to Assess Safety and Tolerability and to Explore Efficacy of NSC001 in Mild to Moderate Alzheimer's Disease
Alzheimer Disease
NSC-Therapeutics90 enrolled10 locationsNCT06995573
Recruiting
Phase 2
Fisetin in Mild Alzheimer's Disease
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 2
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Alzheimer DiseaseCognitively Healthy People
Massachusetts Institute of Technology150 enrolled1 locationNCT07496918
Recruiting
Phase 2
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Alzheimer DiseaseMild Cognitive Impairment
Chang Gung Memorial Hospital80 enrolled1 locationNCT06467539
Recruiting
Phase 2
Levetiracetam for Persons at Risk for Alzheimer's Disease
Hippocampal HyperactivationProdromal Alzheimer Disease
Sunnybrook Health Sciences Centre40 enrolled2 locationsNCT07477431
Recruiting
Phase 2
Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease
Alzheimer DementiaLate Onset Alzheimer DiseaseNeurodegenerative Diseases
University of Arizona100 enrolled10 locationsNCT04838301
Recruiting
Phase 1Phase 2
Nicotinic Acid for the Treatment of Alzheimer's Disease
Alzheimer Disease
Indiana University30 enrolled1 locationNCT06582706