Early Phase 1 Alzheimer Disease Clinical Trials

11 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 111 of 11 trials

Recruiting
Early Phase 1

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

Mild Cognitive ImpairmentMild Alzheimer Disease
Mclean Hospital50 enrolled1 locationNCT04430517
Recruiting
Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1

Investigator Initiated Trial of Galcanezumab Treatment in Alzheimer's Disease

Alzheimer Disease
Xuanwu Hospital, Beijing10 enrolled1 locationNCT07323927
Recruiting
Early Phase 1

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

Cognitive ChangeSleepMild Cognitive Impairment+2 more
University of Pittsburgh116 enrolled1 locationNCT05138848
Recruiting
Early Phase 1

Intravenous Infusion of Umbilical Cord Blood as an Adjunctive Treatment for Alzheimer's Disease

Alzheimer Disease (AD)
Anhui Provincial Hospital30 enrolled1 locationNCT07208344
Recruiting
Early Phase 1

Near-Infrared Light Therapy Combined With Lecanemab for Mild Alzheimer's Disease

Alzheimer Disease
Xuanwu Hospital, Beijing20 enrolled1 locationNCT06992804
Recruiting
Early Phase 1

Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

Alzheimer Disease
Baylor College of Medicine52 enrolled1 locationNCT04740580
Recruiting
Early Phase 1

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

AnxietyAlzheimer DiseaseMild Cognitive Impairment (MCI) Due to Alzheimer's Disease+1 more
Mclean Hospital12 enrolled1 locationNCT04075435
Recruiting
Early Phase 1

Neuroinflammation Imaging in AD

Healthy VolunteerAlzheimer Disease
University of Pennsylvania20 enrolled1 locationNCT04274998
Recruiting
Early Phase 1

Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia

DementiaAlzheimer DiseaseProgressive Aphasia+3 more
University of Texas at Austin120 enrolled1 locationNCT06511752