Phase 2 Amyloid Clinical Trials
33 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 33 trials
Recruiting
Phase 2
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy
Alnylam Pharmaceuticals200 enrolled57 locationsNCT06393712
Recruiting
Phase 1Phase 2
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Relapsed/Refractory Systemic Light Chain Amyloidosis
Regeneron Pharmaceuticals220 enrolled19 locationsNCT06292780
Recruiting
Phase 2
A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis
AL Amyloidosis
European Myeloma Network B.V.30 enrolled10 locationsNCT06649695
Recruiting
Phase 2
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
AmyloidosisTransthyretin Amyloidosis
Oregon Health and Science University150 enrolled1 locationNCT05758493
Recruiting
Phase 2
Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial
AL Amyloidosis
Mayo Clinic96 enrolled2 locationsNCT05898646
Recruiting
Phase 1Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
AmyloidosisLight Chain AmyloidosisRelapsed AL Amyloidosis+1 more
Alexion Pharmaceuticals, Inc.91 enrolled18 locationsNCT07081646
Recruiting
Phase 2
BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis
Systemic Light Chain Amyloidosis
Institute of Hematology & Blood Diseases Hospital, China21 enrolled1 locationNCT07151690
Recruiting
Phase 1Phase 2
Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis
AL Amyloidosis
Brigham and Women's Hospital49 enrolled1 locationNCT06569147
Recruiting
Phase 2
A Study of AMDX-2011P in Participants With CAA
Cerebral Amyloid Angiopathy
Amydis Inc.25 enrolled1 locationNCT05709314
Recruiting
Phase 1Phase 2
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
AmyloidosisAL Amyloidosis
University of Texas Southwestern Medical Center37 enrolled3 locationsNCT05145816
Recruiting
Phase 1Phase 2
Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients
Systemic Light Chain Amyloidosis
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.70 enrolled23 locationsNCT07266116
Recruiting
Phase 2
Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
Multiple MyelomaAmyloidosis
University of Alabama at Birmingham40 enrolled1 locationNCT04991103
Recruiting
Phase 2
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+26 more
Mayo Clinic27 enrolled1 locationNCT07285044
Recruiting
Phase 1Phase 2
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
Immunoglobulin Light Chain (AL) Amyloidosis
AbbVie76 enrolled21 locationsNCT06158854
Recruiting
Phase 1Phase 2
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Beta-AmyloidProdromal Alzheimer's DiseaseAmyloid Plaque+1 more
AC Immune SA176 enrolled19 locationsNCT05462106
Recruiting
Phase 2
Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis
Primary Light-Chain Amyloidosis
Keymed Biosciences Co.Ltd90 enrolled2 locationsNCT07039578
Recruiting
Phase 2
Teclistamab-Daratumumab in AL Amyloidosis
Amyloid Light-chain Amyloidosis
Suzanne Lentzsch, MD25 enrolled1 locationNCT07110844
Recruiting
Phase 2
A Study of AT-02 in Subjects With Systemic Amyloidosis.
Amyloidosis; Systemic
Attralus, Inc.120 enrolled4 locationsNCT05951049
Recruiting
Phase 2
Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis
AL Amyloidosis
Peking Union Medical College Hospital35 enrolled1 locationNCT07079423
Recruiting
Phase 1Phase 2
Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis
Light Chain (AL) Amyloidosis
Nexcella Inc.40 enrolled18 locationsNCT06097832