APL Clinical Trials in Boston, Massachusetts

21 recruitingBoston, Massachusetts

Showing 120 of 21 trials

Recruiting

Targeted Pediatric High-Grade Glioma Therapy

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hodgkin LymphomaNon-Hodgkin LymphomaHematologic Malignancies+14 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting
Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled155 locationsNCT06765109
Recruiting
Not Applicable

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

AnarthriaAmyotrophic Lateral SclerosisSpinal Cord Injuries+5 more
Leigh R. Hochberg, MD, PhD.3 enrolled2 locationsNCT05724173
Recruiting
Not Applicable

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Amyotrophic Lateral SclerosisSpinal Cord Injurieslocked-in Syndrome+3 more
Leigh R. Hochberg, MD, PhD.27 enrolled6 locationsNCT00912041
Recruiting
Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled20 locationsNCT05843253
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+27 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting
Phase 1

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

EpendymomaAnaplastic Ependymoma
M.D. Anderson Cancer Center48 enrolled2 locationsNCT03750513
Recruiting
Phase 2

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms TumorRecurrent Kidney Wilms TumorStage II Kidney Wilms Tumor+2 more
Children's Oncology Group256 enrolled204 locationsNCT04322318
Recruiting
Not Applicable

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

StrokeAmyotrophic Lateral SclerosisDysarthria+3 more
Paradromics2 enrolled3 locationsNCT07357428
Recruiting
Phase 3

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Lymphoma, T-CellPeripheral T-Cell Lymphoma, Not Otherwise SpecifiedAngioimmunoblastic T-cell Lymphoma+4 more
Corvus Pharmaceuticals, Inc.150 enrolled34 locationsNCT06561048
Recruiting

Spastic Paraplegia - Centers of Excellence Research Network

Neuromuscular DiseasesPrimary Lateral SclerosisHereditary Spastic Paraplegia+6 more
Boston Children's Hospital100 enrolled11 locationsNCT06553976
Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

Hereditary Spastic ParaplegiaSPG47SPG50+8 more
Boston Children's Hospital700 enrolled1 locationNCT04712812
Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Movement DisordersMotor Neuron DiseaseHereditary Spastic Paraplegia+3 more
Boston Children's Hospital200 enrolled1 locationNCT05354622
Recruiting
Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Phase 2

Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

Severe Aplastic Anemia
Medical College of Wisconsin60 enrolled25 locationsNCT06517641
Recruiting
Phase 1Phase 2

JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency

Phelan-McDermid SyndromeSHANK3 Haploinsufficiency
Jaguar Gene Therapy, LLC6 enrolled3 locationsNCT06662188
Recruiting
Not Applicable

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

ALSSpinal Cord InjuriesCervical Spinal Cord Injury+2 more
Leigh R. Hochberg, MD, PhD.2 enrolled1 locationNCT06511934
Recruiting
Phase 1

XL092 and Cemiplimab in BRAF WT Thyroid Cancer

Thyroid CancerBRAF Mutation-Related TumorsAnaplastic Thyroid Cancer
UNC Lineberger Comprehensive Cancer Center12 enrolled2 locationsNCT06902376
Recruiting
Early Phase 1

Implantable Microdevice In Primary Brain Tumors

GlioblastomaAstrocytomaGrade II Glioma+5 more
Oliver Jonas12 enrolled1 locationNCT04135807