Phase 1 Asthma Clinical Trials
29 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 29 trials
Recruiting
Phase 1
A Study of CDX-622 in Participants With Mild to Moderate Asthma
Mild to Moderate Asthma
Celldex Therapeutics12 enrolled4 locationsNCT07330778
Recruiting
Phase 1
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
AsthmaCOPDCystic Fibrosis+4 more
Mario Castro, MD, MPH260 enrolled1 locationNCT04624490
Recruiting
Phase 1
A Study to Investigate How Budesonide and Formoterol Move Through the Body (Pharmacokinetics) When Delivered With Different Devices in Participants Aged 4 to Less Than 12 Years Old With Asthma
Asthma
AstraZeneca12 enrolled6 locationsNCT07433569
Recruiting
Phase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Asthma
Amgen124 enrolled21 locationsNCT06637371
Recruiting
Phase 1Phase 2
RIG 101 Trial in Healthy Adults and Adults With Asthma
healthy adult participantsSafety and EfficacyAsthma Exacerbation
RIGImmune Inc.82 enrolled2 locationsNCT07488897
Recruiting
Phase 1Phase 2
Study of PRA-216 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Mild to Moderate Asthma
Prana Therapies Inc96 enrolled7 locationsNCT07245368
Recruiting
Phase 1Phase 2
Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma
Allergic AsthmaAllergic Rhinitis
University of Zurich36 enrolled1 locationNCT06960382
Recruiting
Phase 1
A Study to Evaluate the Safety and Tolerability of Multiple Dose of IBI3002 in Patients With Asthma
Asthma
The First Affiliated Hospital of Soochow University12 enrolled1 locationNCT07015749
Recruiting
Phase 1
A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive
AsthmaMild Asthma
GlaxoSmithKline84 enrolled1 locationNCT06433921
Recruiting
Phase 1
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Asthma
Benjamin Medoff313 enrolled1 locationNCT00595491
Recruiting
Phase 1
The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges
AsthmaChronic Cough (CC)
McMaster University33 enrolled1 locationNCT07085975
Recruiting
Phase 1
A Study to Evaluate the Safety and Tolerability of Multiple Dose of IBI3002 in Healthy and Asthmatic Participants
Asthma
Innovent Biologics (Suzhou) Co. Ltd.60 enrolled1 locationNCT06947408
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Pulmonary Diseases
AsthmaChronic Obstructive Pulmonary DiseasePulmonary Disease
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled1 locationNCT05147688
Recruiting
Phase 1
A Single Ascending Dose/Multiple Ascending Dose Study of JNJ-95597528 in Healthy Participants and a Proof of Mechanism Study in Participants with Mild to Moderate Asthma
AsthmaAtopic Dermatitis
Janssen Research & Development, LLC76 enrolled1 locationACTRN12624001368527
Active
Phase 1
A first-in-human study of APG333 in healthy participants
Asthma
Apogee Therapeutics, Inc.32 enrolled1 locationACTRN12624001358538
Completed
Phase 1
A First-in-human Study of APG808 in Healthy Participants and in Patients With Mild-to-moderate Asthma
Asthma
Apogee Therapeutics, Inc.52 enrolled1 locationACTRN12624000238572
Completed
Phase 1
Bioequivalence double-blind, randomized, two-parallel-group phase 1 study of a humanised anti-immunoglobulin E monoclonal antibody BP001 as Lyophilized Powder Formulation Compared with the Standard Omalizumab (Xolair®) Lyophilized Powder Formulation in healthy male volunteers
Asthma
Biosana Pty Ltd84 enrolled2 locationsACTRN12619000465156
Completed
Phase 1
Phase I trial to evaluate the safety and tolerability of GDC-4379 in healthy volunteers and patients with mild asthma
Asthma
Genentech136 enrolled1 locationACTRN12619000227190
Completed
Phase 1
Phase I trial to evaluate the safety and tolerability of GDC-0214 in healthy volunteers and patients with mild asthma
Asthma
Genentech, Inc.102 enrolled1 locationACTRN12617001227381
Completed
Phase 1
A Phase I randomized blinded single dose comparison of the safety pharmacokinetics and pharmacodynamics of SYN008 and omalizumab (Xolair) in healthy adult subjects
Moderate to severe persistent asthmaChronic idiopathic urticaria
Clinical Network Services (CNS) Pty Ltd80 enrolled1 locationACTRN12616000145404