Phase 3 Asthma Clinical Trials

65 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 65 trials

Recruiting
Phase 3

A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)

Severe Asthma
Generate Biomedicines786 enrolled35 locationsNCT07276724
Recruiting
Phase 3

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Asthma
Teva Branded Pharmaceutical Products R&D LLC724 enrolled175 locationsNCT06664619
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma

Asthma
Novartis Pharmaceuticals200 enrolled62 locationsNCT05562466
Recruiting
Phase 3

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Asthma
AstraZeneca440 enrolled140 locationsNCT06307665
Recruiting
Phase 3

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Asthma
AstraZeneca231 enrolled143 locationsNCT06023589
Recruiting
Phase 3

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

Asthma
AstraZeneca200 enrolled116 locationsNCT05692180
Recruiting
Phase 3

Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab

Severe Asthma
AstraZeneca400 enrolled76 locationsNCT07363642
Recruiting
Phase 3

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma

Asthma
AstraZeneca790 enrolled102 locationsNCT06471257
Recruiting
Phase 3

A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

Severe Asthma
Generate Biomedicines786 enrolled14 locationsNCT07359846
Recruiting
Phase 3

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

Eosinophilic Asthma
AstraZeneca400 enrolled160 locationsNCT06750289
Recruiting
Phase 3

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations

Asthma
Teva Branded Pharmaceutical Products R&D LLC2,700 enrolled393 locationsNCT06052267
Recruiting
Phase 3

A Phase III Study of CM326 in Subjects With Moderate to Severe Asthma

Moderate to Severe Asthma
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.230 enrolled1 locationNCT07372287
Recruiting
Phase 3

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

Asthma
GlaxoSmithKline150 enrolled43 locationsNCT06979323
Recruiting
Phase 3

A Histamine Pharmacodynamic Biomarker to Guide Treatment in Pediatric Asthma (HAS3)

Allergic Asthma
Bridgette Jones300 enrolled1 locationNCT04699604
Recruiting
Phase 3

SIM0718 Treatment of Asthma Clinical Study

Asthma; Eosinophilic
Simcere Pharmaceutical Co., Ltd418 enrolled1 locationNCT06488755
Recruiting
Phase 3

Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

AsthmaWheezing
Sanofi90 enrolled74 locationsNCT06191315
Recruiting
Phase 3

A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in Asthma

Asthma Control
Université de Sherbrooke150 enrolled5 locationsNCT07309614
Recruiting
Phase 3

Anti-Inflammatory Reliever South Africa

Asthma
University of KwaZulu1,038 enrolled2 locationsNCT06429475
Recruiting
Phase 3

Efficacy and Safety Study of 610 in Patients With Severe Asthma

Asthma
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.480 enrolled1 locationNCT06323213
Recruiting
Phase 2Phase 3

Azithromycin for Critical Asthma - Pediatrics

Critical IllnessPediatric Asthma
Johns Hopkins All Children's Hospital100 enrolled1 locationNCT06223828