Orthostatic Hypotension Clinical Trials

4 recruiting

Frequently Asked Questions

Common questions about Orthostatic Hypotension clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting

Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals

Autonomic DysfunctionHypertensionOrthostatic Hypotension
University Medical Centre Ljubljana120 enrolled1 locationNCT07482462
Recruiting
Phase 1Phase 2

Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease.

Parkinson DiseaseOrthostatic Hypotension, DysautonomicMulti-system Atrophy - Parkinsonian Type
Julien Bally36 enrolled2 locationsNCT06831500
Recruiting
Early Phase 1

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center31 enrolled1 locationNCT04620382
Recruiting
Not Applicable

Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease

Parkinson's DiseaseHypotension SymptomaticOrthostatic Hypotension, Dysautonomic+2 more
Ecole Polytechnique Fédérale de Lausanne5 enrolled1 locationNCT06920134
Recruiting
Not Applicable

CPAP for the Treatment of Supine Hypertension

Multiple System AtrophyParkinson DiseaseAutonomic Failure+3 more
Vanderbilt University Medical Center59 enrolled1 locationNCT05489575
Recruiting
Phase 1

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center34 enrolled1 locationNCT02897063
Recruiting
Not Applicable

Blood Pressure Effects on Cognition and Brain Blood Flow in PD

DysautonomiaParkinson DiseaseOrthostatic Hypotension
University of California, San Diego60 enrolled1 locationNCT05400174
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915
Recruiting
Not Applicable

The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients

Orthostatic Hypotension
Zeng Changhao80 enrolled1 locationNCT06255717