AxSpA Clinical Trials

14 recruitingLast updated: June 18, 2026

There are 14 actively recruiting axspa clinical trials across 15 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4. Top locations include Créteil, France, Paris, France, Berlin, Germany. Updated daily from ClinicalTrials.gov.


AxSpA Trials at a Glance

14 actively recruiting trials for axspa are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Créteil, Paris, and Berlin. Lead sponsors running axspa studies include University of Bonn, Assistance Publique - Hôpitaux de Paris, and Adelphi Real World.

Browse axspa trials by phase

Treatments under study

About AxSpA Clinical Trials

Looking for clinical trials for AxSpA? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new AxSpA trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about AxSpA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Phase 1Phase 2

EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)

Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled15 locationsNCT07047703
Recruiting

A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Upadacitinib in a Real-world Setting

Axial Spondylarthritis (r-axSpA)
AbbVie352 enrolled72 locationsNCT05094128
Recruiting
Phase 2

A Study of SPY072 in Rheumatic Disease

Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting
Phase 2Phase 3

The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.

Axial Spondylarthritis (axSpA)IgG4-related DiseaseInflammation of Unknown Origin+1 more
Universitaire Ziekenhuizen KU Leuven140 enrolled1 locationNCT07535554
Recruiting

Biomarkers in Ankylosing Spondylitis

Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
Kirsehir Ahi Evran Universitesi160 enrolled1 locationNCT07117344
Recruiting

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

Celiac DiseaseMultiple SclerosisAnkylosing Spondylitis+6 more
TScan Therapeutics, Inc.300 enrolled12 locationsNCT06587828
Recruiting
Not Applicable

Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)

Axial Spondyloarthritis (AxSpA)
Assistance Publique - Hôpitaux de Paris72 enrolled5 locationsNCT06083090
Recruiting
Phase 4

REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Axial Spondyloarthritis (AxSpA)
Sint Maartenskliniek200 enrolled7 locationsNCT07160231
Recruiting

Treatment Effectiveness in People With axSpA or PsA Starting Treatment With Bimekizumab, Risankizumab, Guselkumab, Upadacitinib, or a TNF Inhibitor

Psoriatic Arthritis (PsA)Axial Spondylarthritis (axSpA)
Adelphi Real World700 enrolled1 locationNCT07166315
Recruiting

Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Sclerosis (SSc)+10 more
University of Bonn120 enrolled1 locationNCT07150000
Recruiting
Not Applicable

Initial Standardized Global Review in Axial Spondyloarthritis

Axial Spondylarthritis (axSpA)
Association de Recherche Clinique en Rhumatologie154 enrolled21 locationsNCT07141017
Recruiting

A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS

Axial SpondyloarthritisAxial Spondyloarthritis (AxSpA)Axial Spondyloarthritis, Non-Radiographic+4 more
University of Bonn50 enrolled1 locationNCT06807853
Recruiting
Not Applicable

axSEND: Exploring Immune and Microbiota Effects of a Partial Enteral Nutrition Diet in Axial Spondyloarthritis

DysbiosisAnkylosing SpondylitisArthritis+6 more
NHS Greater Glasgow and Clyde62 enrolled2 locationsNCT06460805
Recruiting

German Spondyloarthritis Inception Cohort

Ulcerative Colitis (UC)Crohn Disease (CD)Non-radiographic Axial Spondyloarthritis (Nr-axSpA)+3 more
Charite University, Berlin, Germany1,000 enrolled1 locationNCT01277419