Arthritis Clinical Trials

40 recruiting

Arthritis Trials at a Glance

959 actively recruiting trials for arthritis are listed on ClinicalTrialsFinder across 6 cities in 69 countries. The largest study group is Not Applicable with 370 trials, with the heaviest enrollment activity in Chicago, Paris, and Houston. Lead sponsors running arthritis studies include Istituto Ortopedico Rizzoli, Assistance Publique - Hôpitaux de Paris, and Riphah International University.

Treatments under study

About Arthritis Clinical Trials

Looking for clinical trials for Arthritis? There are currently 40 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Arthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Arthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 959 trials

Recruiting

Natural History and Development of Spondyloarthritis

ArthritisSpondylitis, Ankylosing
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)2,000 enrolled1 locationNCT01422694
Recruiting
Phase 1

A Study of AZD0120 in Autoimmune Diseases

Rheumatoid ArthritisIdiopathic Inflammatory MyopathiesSystemic Sclerosis
AstraZeneca27 enrolled18 locationsNCT07295847
Recruiting
Phase 1

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Hidradenitis SuppurativaPsoriatic ArthritisAxial Spondyloarthritis+1 more
UCB Biopharma SRL20 enrolled12 locationsNCT06888193
Recruiting
Phase 1

An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis
Novartis Pharmaceuticals57 enrolled14 locationsNCT07029555
Recruiting

Prospective Validation of a Pharmacological Biomarker for Low-Dose Rituximab in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
University Hospital, Tours30 enrolled1 locationNCT06933134
Recruiting

dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound

Rheumatoid ArthritisInterstitial Lung DiseaseThoracic Ultrasound+1 more
University Hospital, Tours280 enrolled1 locationNCT06235645
Recruiting
Phase 2

A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Juvenile Idiopathic Arthritis
Sanofi51 enrolled31 locationsNCT02991469
Recruiting

Studies of the Natural History of Rheumatic Diseases

ArthritisRheumatic Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)7,500 enrolled1 locationNCT00024479
Recruiting
Not Applicable

Use of a Putty as Gap Filler in Open-wedge Osteotomy

Osteo Arthritis Knee
UMC Utrecht40 enrolled1 locationNCT05992038
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

Knee Osteoarthritis
Doron Therapeutics Inc.260 enrolled17 locationsNCT07219771
Recruiting
Phase 3

A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.

Osteoarthritis, Knee
Paradigm Biopharmaceuticals Ltd.466 enrolled52 locationsNCT06917404
Recruiting

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

Rheumatoid ArthritisFibromyalgia
University of Florida150 enrolled1 locationNCT05277025
Recruiting

Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease

Rheumatoid ArthritisInterstitial Lung Disease
University of Colorado, Denver750 enrolled1 locationNCT03297775
Recruiting

The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions

VasculitisSystemic Lupus Erthematosus (SLE)Rheumatic Diseases+3 more
McGill University Health Centre/Research Institute of the McGill University Health Centre100 enrolled1 locationNCT07278609
Recruiting
Phase 1

Efficacy and Safety of HN2301 in Autoimmune Diseases(AIDs)

Rheumatoid ArthritisSclerodermaSystemic Lupus Erythematosus
Shenzhen MagicRNA Biotechnology Co., Ltd30 enrolled1 locationNCT06801119
Recruiting
Not Applicable

Comparison of Distal IPACK and Popliteal Plexus Block Combined With Femoral Triangle Block After Total Knee Arthroplasty

Osteo Arthritis of the Knee
Karaman Training and Research Hospital120 enrolled1 locationNCT07130552
Recruiting
Not Applicable

Modifying PEST for Psoriatic Arthritis Screening

Psoriatic ArthritisPlaque Psoriasis
Novartis Pharmaceuticals502 enrolled21 locationsNCT06382051
Recruiting
Phase 1

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

Rheumatoid ArthritisSystemic Lupus ErythematosusIdiopathic Inflammatory Myopathies
AstraZeneca72 enrolled35 locationsNCT06916806
Recruiting
Phase 4

Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis

Knee Osteoarthritis
Northwestern University180 enrolled1 locationNCT06245109
Recruiting

RETRO-PROSPECTIVE POSTMARKET CLINICAL STUDY FOR FX SHOULDER SOLUTIONS SHOULDER SYSTEMS

Glenohumeral OsteoarthritisAvascular Necrosis of the Head of HumerusHumeral Fracture, Proximal
FX Solutions1,004 enrolled22 locationsNCT07558590