Arthritis Clinical Trials

1,156 recruitingLast updated: July 17, 2026

There are 1,156 actively recruiting arthritis clinical trials across 74 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Chicago, Illinois, United States, New York, New York, United States, Paris, France. Updated daily from ClinicalTrials.gov.


Arthritis Trials at a Glance

1,156 actively recruiting trials for arthritis are listed on ClinicalTrialsFinder across 6 cities in 74 countries. The largest study group is Not Applicable with 471 trials, with the heaviest enrollment activity in Chicago, New York, and Paris. Lead sponsors running arthritis studies include Istituto Ortopedico Rizzoli, Assistance Publique - Hôpitaux de Paris, and Poznan University of Medical Sciences.

Treatments under study

About Arthritis Clinical Trials

Looking for clinical trials for Arthritis? There are currently 42 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Arthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Arthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,156 trials

Recruiting
Not Applicable

Modifying PEST for Psoriatic Arthritis Screening

Psoriatic ArthritisPlaque Psoriasis
Novartis Pharmaceuticals502 enrolled30 locationsNCT06382051
Recruiting

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

ArthritisStill's Disease, Adult-OnsetSystemic Inflammation+1 more
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)2,000 enrolled1 locationNCT03510442
Recruiting
Not Applicable

Cannabinoids for Osteoarthritis Pain Effectiveness Trial

osteoarthritis of Knee.Osteoarthritis, Hip
University Health Network, Toronto100 enrolled3 locationsNCT06878417
Recruiting
Phase 1

A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)

Rheumatoid ArthritisHealthy VolunteersSystemic Lupus Erythematosus
Capstan Therapeutics64 enrolled3 locationsNCT06917742
Recruiting
Not Applicable

MOTION Clinical Trial

Osteoarthritis, Knee
Moximed100 enrolled9 locationsNCT06843980
Recruiting
Not Applicable

MISHA Post-Market Clinical Study

Osteo Arthritis Knee
Moximed120 enrolled4 locationsNCT06118892
Recruiting

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Rheumatoid Arthritis (RA)Atherosclerotic Cardiovascular Disease (ASCVD)
Brigham and Women's Hospital120 enrolled3 locationsNCT07315997
Recruiting

Dysphagia in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Tanta University30 enrolled2 locationsNCT07401732
Recruiting

Serum Fetuin-A and COMP Levels in Knee Osteoarthritis

Knee OsteoarthritisOsteoarthritis, Knee
Antalya Training and Research Hospital180 enrolled1 locationNCT07706569
Recruiting
Not Applicable

Genicular Artery Embolization for Knee Osteoarthritis

Knee OsteoarthritisOsteoarthritis
Northwestern University15 enrolled1 locationNCT07537153
Recruiting
Phase 3

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic
MoonLake Immunotherapeutics AG600 enrolled139 locationsNCT06641089
Recruiting
Not Applicable

Pain in Juvenile Arthritis

Juvenile Idiopathic Arthritis
Washington University School of Medicine140 enrolled1 locationNCT07217782
Recruiting
Phase 1Phase 2

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

Total Knee AnthroplastyOsteoarthritis PrimaryBilateral Knee Osteoarthritis+1 more
Unity Health Toronto60 enrolled1 locationNCT06809998
Recruiting
Not Applicable

Vibratory Anesthesia on Pain Following Corticosteroid Injections

ArthropathyBilateral Arthritis of WristCompression Neuropathy+2 more
The University of Texas Medical Branch, Galveston165 enrolled1 locationNCT07553273
Recruiting
Phase 1

Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

Juvenile Psoriatic Arthritis
Novartis Pharmaceuticals20 enrolled8 locationsNCT06751238
Recruiting
Phase 1Phase 2

Phase 1b/2 Study of IV Sarilumab in Adult With RA

Rheumatoid Arthritis
Sanofi140 enrolled2 locationsNCT07704580
Recruiting

Persona Revision Knee System Outcomes

Knee OsteoarthritisInfectionArthroplasty Complications+1 more
Zimmer Biomet380 enrolled16 locationsNCT04821154
Recruiting
Not Applicable

Altered Joint Mechanics and Biological Response in Osteoarthritic Knees.

Knee osteoarthritis (OA)
Universitaire Ziekenhuizen KU Leuven30 enrolled1 locationNCT07481461
Recruiting
Phase 2

Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.

Antibiotic Resistant InfectionOsteoarthritis, HipProsthetic joint infection+1 more
University Hospital, Linkoeping1,100 enrolled1 locationNCT05169229
Recruiting
Not Applicable

Prospective Study of Arthrodesis of Finger Distal Interphalangeal Joints Using the Kerifuse Device

Osteoarthritis ThumbOsteoarthritis Finger
Clinique Saint François, Nice, France50 enrolled1 locationNCT06151834