Arthritis Clinical Trials

1,129 recruitingLast updated: June 17, 2026

There are 1,129 actively recruiting arthritis clinical trials across 74 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Chicago, Illinois, United States, New York, New York, United States, Paris, France. Updated daily from ClinicalTrials.gov.


Arthritis Trials at a Glance

1,129 actively recruiting trials for arthritis are listed on ClinicalTrialsFinder across 6 cities in 74 countries. The largest study group is Not Applicable with 455 trials, with the heaviest enrollment activity in Chicago, New York, and Paris. Lead sponsors running arthritis studies include Istituto Ortopedico Rizzoli, Assistance Publique - Hôpitaux de Paris, and Poznan University of Medical Sciences.

Treatments under study

About Arthritis Clinical Trials

Looking for clinical trials for Arthritis? There are currently 42 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Arthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Arthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,129 trials

Recruiting
Phase 1

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

Rheumatoid ArthritisSystemic Lupus Erythematosus
AbbVie30 enrolled6 locationsNCT07607964
Recruiting
Phase 2

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
AbbVie180 enrolled97 locationsNCT06972446
Recruiting
Not Applicable

Percutaneous Neurostimulation in Knee Osteoarthritis

NeuromodulationOsteoarthritis(OA) of the knee
Tanta University100 enrolled1 locationNCT07637682
Recruiting

Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis

Knee OsteoarthritisHyaluronic AcidPlatelet-Rich Plasma
Centre Hospitalier Universitaire, Amiens100 enrolled1 locationNCT05039463
Recruiting
Not Applicable

Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial

Knee Osteoarthritis
University of California, Davis90 enrolled2 locationsNCT04472702
Recruiting
Not Applicable

Preoperative Fasting and the Gut Microbiome Before Hip Replacement

Surgical wound infectionPostoperative ComplicationsGastrointestinal Microbiome+2 more
Charite University, Berlin, Germany130 enrolled1 locationNCT07651462
Recruiting
Phase 2

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis
Merck Sharp & Dohme LLC315 enrolled100 locationsNCT07133633
Recruiting

Registry of Outcomes of Dezawa MuseCells®

longevityOsteoarthritis (OA)Pain+2 more
MuseCell Innovations Pte LTD5,000 enrolled2 locationsNCT07645989
Recruiting
Not Applicable

Efficacy of Therapy With PRP Injections Versus HA in Patients With Advanced Grade of GONArthrosis

Knee Osteoarthritis
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer150 enrolled1 locationNCT07016672
Recruiting
Phase 2

Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

Psoriatic Arthritis
Merck Sharp & Dohme LLC140 enrolled43 locationsNCT07486960
Recruiting
Phase 2

Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.

Patellofemoral osteoarthritis
University Hospital, Basel, Switzerland75 enrolled9 locationsNCT06163573
Recruiting
Phase 3

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic
MoonLake Immunotherapeutics AG600 enrolled138 locationsNCT06641089
Recruiting
Phase 1

R-2487 in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid
Rise Therapeutics LLC73 enrolled6 locationsNCT05961592
Recruiting

Heidelberg Registry for Hip and Knee Joint Implants and Revisions

arthroplastyOsteoarthritis
University Hospital Heidelberg10,000 enrolled1 locationNCT06850818
Recruiting

Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Primary Hip Prosthesis System

Osteoarthritis (OA) of the hipTotal Hip Arthroplasty (THA)Joint Diseases+2 more
TIPMED Medical Device Manufacturing Ltd. Co.101 enrolled4 locationsNCT07651735
Recruiting
Not Applicable

Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial

Osteoarthritis, Knee
Mayo Clinic128 enrolled1 locationNCT06887829
Recruiting
Phase 3

Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib for the Treatment of Polyarticular-course Juvenile Idiopathic Arthritis in Children and Adolescents

Polyarticular Course Juvenile Idiopathic Arthritis
Alfasigma S.p.A.65 enrolled14 locationsNCT07554495
Recruiting
Not Applicable

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

ArthritisUnstable Radial HeadProximal Radioulnar Joint Instability+1 more
Aptis Medical84 enrolled7 locationsNCT05796908
Recruiting
Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 4

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

Psoriatic ArthritisOverweight or Obesity
Eli Lilly and Company200 enrolled55 locationsNCT06864026