Phase 2 Biliary Tract Cancer Clinical Trials
48 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 48 trials
Recruiting
Phase 2
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Colorectal, CancerGastric CancerBiliary Tract Cancer+4 more
AstraZeneca454 enrolled96 locationsNCT05489211
Recruiting
Phase 1Phase 2
Study for AZD4360 in Participants With Advanced Solid Tumours
Gastric CancerGastroesophageal-junction CancerBiliary Tract Cancer+1 more
AstraZeneca117 enrolled18 locationsNCT06921928
Recruiting
Phase 1Phase 2
Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer
Biliary Tract CancerCholangiocarcinomaExtrahepatic Cholangiocarcinoma+2 more
Beijing Biotech30 enrolled1 locationNCT07641036
Recruiting
Phase 1Phase 2
Hepatic Arterial Infusion Chemotherapy Plus Envafolimab and Lenvatinib for First-Line Unresectable Advanced Biliary Tract Cancer
Biliary Tract Cancer
West China Hospital20 enrolled1 locationNCT07636798
Recruiting
Phase 2
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
Biliary Tract Cancer
UNICANCER72 enrolled41 locationsNCT06529718
Recruiting
Phase 1Phase 2
AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Lung CancersUrothelial CancerLocally Advanced+5 more
Avenzo Therapeutics, Inc.480 enrolled18 locationsNCT07038343
Recruiting
Phase 1Phase 2
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Breast CancerEsophageal CancerPancreatic Cancer+13 more
ModeX Therapeutics, An OPKO Health Company285 enrolled6 locationsNCT06239194
Recruiting
Phase 2
Alternating HAIC and Systemic Chemotherapy With or Without Adebrelimab and Apatinib for Unresectable Biliary Tract Cancer
Biliary Tract Cancer
Air Force Military Medical University, China124 enrolled1 locationNCT07569679
Recruiting
Phase 2
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
Biliary Tract CancerHepatocellular Carcinoma
AstraZeneca294 enrolled60 locationsNCT05775159
Recruiting
Phase 1Phase 2
HX009+ IN10018 With or Without Standard Chemotherapy for Advanced Solid Tumours
Biliary Tract CancerMelanoma
Hangzhou Hanx Biopharmaceuticals, Ltd.124 enrolled1 locationNCT06708663
Recruiting
Phase 2
Phase II Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Albumin-Bound Paclitaxel and Lenvatinib as Second-Line Therapy for Unresectable or Metastatic Biliary Tract Cancer
Second-Line Therapy for Unresectable or Metastatic Biliary Tract Cancer
Sun Yat-sen University40 enrolled1 locationNCT07530445
Recruiting
Phase 1Phase 2
A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer
Biliary Tract Cancer
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.102 enrolled43 locationsNCT06431490
Recruiting
Phase 2
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
Biliary Tract CancerHepatocellular Carcinoma
Replimune, Inc.60 enrolled12 locationsNCT05733598
Recruiting
Phase 2
A Study of SHR-A1904 in Previous Systemic Treatment Failed Biliary Tract Cancer
Biliary Tract Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.151 enrolled2 locationsNCT07450976
Recruiting
Phase 2
Trastuzumab in Combination With Serplulimab and Chemotherapy for the Treatment of HER2-overexpressing Unresectable Locally Advanced or Metastatic Biliary Tract Cancer or Urothelial Carcinoma After Failure of Standard Therapy
Biliary Tract CancerUrothelial CarcinomaHER2
Xiujuan Qu20 enrolled1 locationNCT07506057
Recruiting
Phase 1Phase 2
A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer
Biliary Tract Cancer
Akeso135 enrolled1 locationNCT06938321
Recruiting
Phase 2
Ligufalimab and Cadonilimab in Advanced Liver Cancers
Biliary Tract CancerAdvanced Hepatocellular CarcinomaRefractory Hepatocellular Carcinoma
University of Texas Southwestern Medical Center64 enrolled1 locationNCT06789848
Recruiting
Phase 2
Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer
Biliary Tract CancerCholangiocarcinomaGallbladder Cancer+2 more
Case Comprehensive Cancer Center27 enrolled2 locationsNCT07146646
Recruiting
Phase 2
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Gastric CancerGastroesophageal-junction CancerBiliary Tract Cancer+1 more
AstraZeneca224 enrolled52 locationsNCT06219941
Recruiting
Phase 2
Cosiporfin Sodium for Injection Photodynamic Therapy
Biliary Tract Cancers (BTC)
Shanghai Guangsheng Biopharmaceutical Co., Ltd30 enrolled1 locationNCT07398339