Phase 2 Breast Cancer Stage I Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 2

Trastuzumab Deruxtecan in First-Line HER2-Positive Metastatic Breast Cancer With Proactive Toxicity Management

Breast Cancer Stage IV
SOLTI Breast Cancer Research Group300 enrolled27 locationsNCT07371585
Recruiting
Phase 2

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

Breast CancerHER2-positive Breast CancerBreast Cancer Stage IV
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07459673
Recruiting
Phase 2

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

Breast CancerBreast CarcinomaBreast Neoplasm+34 more
University of California, Davis86 enrolled1 locationNCT06268665
Recruiting
Phase 2

Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)

Breast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III
George Washington University90 enrolled1 locationNCT06806930
Recruiting
Phase 2

Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer

Breast CancerBreast Cancer Stage IIBreast Cancer Invasive+2 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's40 enrolled2 locationsNCT07188246
Recruiting
Phase 1Phase 2

A Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC.

Metastatic Breast CancerLocally Advanced Breast CancerBreast Cancer Stage IV+1 more
Forward Pharmaceuticals Co., Ltd.99 enrolled22 locationsNCT06064812
Recruiting
Phase 1Phase 2

A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC

Metastatic Breast CancerBreast Cancer Stage IBreast Cancer Stage II+2 more
Forward Pharmaceuticals Co., Ltd.196 enrolled1 locationNCT07002177
Recruiting
Phase 2

Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases

Breast Cancer Stage IV
Medical University of Vienna20 enrolled1 locationNCT05866432
Recruiting
Phase 2

TRUDI: TDXD+Durva in HER2+/Low IBC

Breast CancerInvasive Breast CancerHER2-positive Breast Cancer+2 more
Filipa Lynce, MD63 enrolled3 locationsNCT05795101
Recruiting
Phase 2

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

Breast CancerBreast Cancer Stage IBreast Cancer Stage II+5 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06727773
Recruiting
Phase 2Phase 3

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

Breast CancerBreast Cancer Stage IBreast Cancer Stage II+1 more
University of Virginia45 enrolled1 locationNCT05288777
Recruiting
Phase 2

Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer

Breast Cancer Stage II
SOLTI Breast Cancer Research Group1,100 enrolled51 locationsNCT05296746
Recruiting
Phase 2

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Breast CancerBreast Cancer FemaleBreast Neoplasm+3 more
Baylor Breast Care Center185 enrolled2 locationsNCT05020860
Recruiting
Phase 2

HR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Sacituzumab Govitecan

Breast Cancer Stage IV
SOLTI Breast Cancer Research Group50 enrolled10 locationsNCT06236269
Recruiting
Phase 2

Adjuvant Pyrotinib and Capecitabine For HER2 Positive Micro Invasive Breast Cancer

Breast Cancer Stage I
Fudan University1,008 enrolled1 locationNCT05861271
Completed
Phase 2

Effects of perioperative Recombinant Human Erythropoietin administration on proinflammatory cascade following breast cancer surgery.

Female subjects with breast cancer stage II/III undergoing a modified radical mastectomy
University Hospital of Ioannina22 enrolled1 locationACTRN12610000813088