Early Phase 1 Cancer Clinical Trials
125 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 125 trials
Recruiting
Early Phase 1
Tirzepatide in Obesity-Driven Endometrial Cancer
Endometrial CancerObesity
UNC Lineberger Comprehensive Cancer Center20 enrolled1 locationNCT07065552
Recruiting
Early Phase 1
The Dosimetry, Safety and Diagnostic Efficacy of ⁶⁸Ga-FC516 in Healthy Subjects and Patients With Prostate Cancer
Prostate CancerHealthy Adult
FindCure Biosciences (ZhongShan) Co., Ltd.10 enrolled1 locationNCT07468708
Recruiting
Early Phase 1
Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer
Prostate CancerLocalized Prostate Carcinoma
Ivan de Kouchkovsky, MD80 enrolled1 locationNCT02526368
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Brain CancerGliomaHigh Grade Glioma+1 more
Eben Rosenthal38 enrolled1 locationNCT07210632
Recruiting
Early Phase 1
A Study of a Weight Loss Intervention in People With Endometrial Cancer
Endometrial Cancer
Memorial Sloan Kettering Cancer Center36 enrolled7 locationsNCT06751589
Recruiting
Early Phase 1
Using Aspirin to Improve Immunological Features of Ovarian Tumors
Ovarian CancerFallopian Tube CancerPeritoneal Cancer
H. Lee Moffitt Cancer Center and Research Institute100 enrolled4 locationsNCT05080946
Recruiting
Early Phase 1
Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute16 enrolled1 locationNCT06435351
Recruiting
Early Phase 1
Feasibility Study of Suizenji, in Patients With Unresectable Pancreatic Ductal Adenocarcinoma (SUNRISE-II)
Pancreatic Cancer
SONIRE Therapeutics Inc.10 enrolled1 locationNCT07033689
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Pilot Trial of Supplemental Vitamin A and Nicotinamide
Skin CancerKidney Transplant Recipients
Rhode Island Hospital30 enrolled1 locationNCT05702398
Recruiting
Early Phase 1
Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
Metastatic CancerCarcinomaAdenocarcinoma
Roberto Vargas4 enrolled1 locationNCT05065736
Recruiting
Early Phase 1
INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases
Colorectal Cancer Metastatic
Northwell Health10 enrolled1 locationNCT07172282
Recruiting
Early Phase 1
Feasibility Evaluation of the Muse Magnetic Resonance Guided Focused Ultrasound System
Breast Cancer
University of Utah34 enrolled1 locationNCT05291507
Recruiting
Early Phase 1
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers
Advanced Solid Cancers
Hainan Cancer Hospital10 enrolled1 locationNCT07475182
Recruiting
Early Phase 1
Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+20 more
Ohio State University Comprehensive Cancer Center50 enrolled1 locationNCT05417308
Recruiting
Early Phase 1
Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Pancreatic Cancer
Pancreatic Cancer
Northwell Health10 enrolled1 locationNCT07254091
Recruiting
Early Phase 1
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Early Phase 1
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690