Phase 1 Cannabis Clinical Trials
19 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–19 of 19 trials
Recruiting
Phase 1
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
Cannabis
Yale University100 enrolled1 locationNCT04704271
Recruiting
Phase 1
The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
Cannabis Use
Johns Hopkins University80 enrolled1 locationNCT05602649
Recruiting
Phase 1
Effect of Cannabis on E-Cigarette Use Behavior
Cannabis UseTobacco UseElectronic Cigarette Use
Johns Hopkins University100 enrolled1 locationNCT06609109
Recruiting
Phase 1
Psilocybin-assisted Treatment for Cannabis Use Disorder
Cannabis Use Disorder
Johns Hopkins University12 enrolled1 locationNCT06660381
Recruiting
Phase 1Phase 2
SV2A in Older Adults
Cannabis Use
Yale University24 enrolled1 locationNCT05465538
Recruiting
Phase 1
Effect of Cannabis on Cigarette Use Behavior
Cannabis UseTobacco UseCigarette Smoking
Johns Hopkins University100 enrolled1 locationNCT06609083
Recruiting
Phase 1
Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy Adults
Cannabis, Drug Effects
Food and Drug Administration (FDA)48 enrolled2 locationsNCT07176208
Recruiting
Phase 1Phase 2
Mitigating PTSD-CUD After Sexual Assault
Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1Phase 2
Modulation of THC Effects by CBD: a Dose-ranging Study
CannabisTHC
Centre hospitalier de l'Université de Montréal (CHUM)100 enrolled1 locationNCT06099379
Recruiting
Phase 1Phase 2
SCORE Emerging Adult Cannabis Use & Stress
Cannabis Use Disorder
Medical University of South Carolina148 enrolled1 locationNCT05885542
Recruiting
Phase 1
High Potency Cannabis: Acute and Protracted Effects
PainPharmacokineticsAbuse Cannabis
University of California, Los Angeles30 enrolled1 locationNCT06859723
Recruiting
Phase 1
Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment
Cannabis IntoxicationAlcohol Intoxication
Johns Hopkins University90 enrolled1 locationNCT06293040
Recruiting
Phase 1
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Depression, AnxietyAnxietyDepression - Major Depressive Disorder+1 more
Trustees of Dartmouth College15 enrolled1 locationNCT06920238
Recruiting
Phase 1
Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans
SchizophreniaCannabis Use Disorder
Yale University215 enrolled1 locationNCT06058702
Recruiting
Phase 1
Pharmacokinetics and Pharmacodynamics of CHI-914 in Healthy Participants
Behavioral Pharmacology of Cannabis
Johns Hopkins University30 enrolled1 locationNCT05324982
Recruiting
Phase 1
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans
Cannabis
Yale University100 enrolled1 locationNCT02781519
Recruiting
Phase 1
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
Cannabis
Yale University40 enrolled1 locationNCT02811510
Recruiting
Phase 1
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
Cannabis UseChild Development
University of Colorado, Denver140 enrolled1 locationNCT06379971
Completed
Phase 1
CLIMATE Schools
Alcohol and cannabis misuse
University of New South Wales (UNSW)764 enrolled1 locationACTRN12607000312448