Cardiovascular Clinical Trials in Durham, North Carolina

17 recruitingDurham, North Carolina

Showing 117 of 17 trials

Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled774 locationsNCT07037433
Recruiting
Phase 3

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Cardiovascular Disease
Amgen11,000 enrolled248 locationsNCT07136012
Recruiting

Product Surveillance Registry

Cardiac Rhythm DisordersDigestive disordersMinimally Invasive Surgical Procedures+13 more
Medtronic100,000 enrolled395 locationsNCT01524276
Recruiting
Phase 3

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

HypertensionHigh Risk Cardiovascular DiseaseHigh Cardiovascular Risk
Alnylam Pharmaceuticals11,000 enrolled856 locationsNCT07181109
Recruiting
Phase 2Phase 3

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

Atherosclerotic Cardiovascular Disease in Patients With ESKD
CSL Behring3,110 enrolled547 locationsNCT05485961
Recruiting
Phase 4

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Cardiovascular DiseasesDementiaCognitive Impairment, Mild
Duke University20,000 enrolled103 locationsNCT04262206
Recruiting
Phase 3

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Cardiovascular Disease
AstraZeneca15,100 enrolled1333 locationsNCT07000357
Recruiting
Not Applicable

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

Pulmonary Embolism (Diagnosis)Diagnostic ImagingImplementation Science+7 more
Duke University75 enrolled1 locationNCT07159269
Recruiting
Phase 1

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

HypercholesterolaemiaMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG90 enrolled18 locationsNCT07491172
Recruiting

Global Paradise System US Post Approval Study

Cardiovascular DiseasesHypertensionVascular Diseases
ReCor Medical, Inc.1,000 enrolled39 locationsNCT06297291
Recruiting
Phase 3

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular RiskAcute Myocardial Infarction (AMI)
Novo Nordisk A/S10,000 enrolled970 locationsNCT06118281
Recruiting
Not Applicable

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Heart FailureCardiovascular DiseasesHeart Diseases
BrioHealth Solutions, Inc.780 enrolled37 locationsNCT06310031
Recruiting
Not Applicable

Cardiac Outcomes With Near-Complete Estrogen Deprivation

Breast CancerTriple-Negative Breast CancerCardiovascular Complications
Duke University90 enrolled3 locationsNCT05309655
Recruiting

PKP2-ACM Natural History Study

Genetic diseasesCardiomyopathiesCardiovascular Diseases+1 more
Rocket Pharmaceuticals Inc.36 enrolled3 locationsNCT06644742
Recruiting
Not Applicable

Role of Aging and Individual Variation in Exercise Training Responsiveness

ObesityInsulin ResistanceCardiovascular Diseases+1 more
Duke University26 enrolled1 locationNCT06471569
Recruiting

Observational Pharmaco-Epidemiology Research & Analysis

Cardiovascular DiseasesInflammatory Bowel DiseasesLiver Diseases+4 more
Epividian2,000,000 enrolled1 locationNCT03813862
Recruiting

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

Acute Kidney InjuryIntraabdominal HypertensionAbdominal Compartment Syndrome+1 more
Potrero Medical2,500 enrolled9 locationsNCT04669548