Phase 3 Care Clinical Trials
20 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 20 trials
Recruiting
Phase 3
Canadian Critical Care Comparative Effectiveness Platform
NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled8 locationsNCT06605144
Recruiting
Phase 3
iCare4Me Transitions
Caregiver Stress
University of Pennsylvania314 enrolled3 locationsNCT06167746
Recruiting
Phase 3
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
Intensive Care Units, PediatricAnesthetics, InhalationMechanically Ventilated, Critically Ill Children
Sunnybrook Health Sciences Centre60 enrolled3 locationsNCT05867472
Recruiting
Phase 2Phase 3
Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo
Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Not Yet Recruiting
Phase 3
Ketamine when compared to usual care as induction drugs for tracheal intubation of critically ill patients: A prospective, blinded, parallel-group, randomised, feasibility trial
Critical Care
St Vincent's Hospital (Melbourne) Ltd50 enrolled3 locationsACTRN12624001418561
Recruiting
Phase 3
Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery
Intensive Care Unit Delirium
University of Novi Sad200 enrolled1 locationNCT05849597
Recruiting
Phase 2Phase 3
Muscle growth and anabolism in intensive care survivors
Intensive CareCritical illness nutrition
Sir Charles Gairdner Hospital60 enrolled3 locationsACTRN12623000729628
Completed
Phase 3
Early versus delayed aperient use in the intensive care unit
Bowel management in intensive care
Austin Health880 enrolled1 locationACTRN12623000112662
Recruiting
Phase 3
An Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease
The Study Will Focus on Assessing the Survival Benefit on an Enhanced Package of Care for Patients With Advanced HIV Disease
Makerere University2,400 enrolled1 locationNCT05085171
Not Yet Recruiting
Phase 3
The Role of Oseltamivir During Influenza Outbreaks in Aged-care Facilities in the Context of Optimal Influenza Vaccination and Infection Control
Influenza in Residential Aged Care FacilitiesSurveillance systems for influenza in Residential Aged Care Facilities
Children's Hospital, Westmead: National Centre for Immunisation Research and Surveillance74 enrolled1 locationACTRN12615000638538
Recruiting
Phase 3
The SuDDICU Study of Antibiotic Prophylaxis in Critical Illness
Known or suspected infection in critically ill patients in the Intensive Care Unit (ICU)
The George Institute for Global Health15,000 enrolled18 locationsACTRN12615000411549
Completed
Phase 2Phase 3
Permissive HyperthErmiA Through Avoidance of Paracetamol in Known or Suspected Infection in the Intensive Care Unit (ICU)
Known or suspected infection in critically ill patients in the Intensive Care Unit (ICU)
Medical Research Institute of New Zealand700 enrolled1 locationACTRN12612000513819
Not Yet Recruiting
Phase 2Phase 3
The effect of saline instillation during physiotherapy (SIP) in the intensive care unit - a randomized crossover trial
Critically ill intubated intensive care patients
University of Queensland35 enrolled1 locationACTRN12612000432819
Not Yet Recruiting
Phase 2Phase 3
Sedation Practice in Intensive Care in Australia and New Zealand- A Pilot Study
Sedation in intensive care patients
ANZIC-research centre, Monash University60 enrolled1 locationACTRN12611000166976
Terminated
Phase 3
The Exelon Patch (Transdermal Rivastigmine) for the treatment of severe delirium in elderly subacute care inpatients
Delirium in elderly subacute care inpatients
Melbourne Health60 enrolled1 locationACTRN12609001020279
Completed
Phase 3Phase 4
A prospective, open-label, daily wear, parallel group, randomised clinical trial assessing an investigational contact lens care solution for comfort, safety and efficacy with four commercially available contact lenses, worn bilaterally over three months, in both experienced and new contact lens wearers
Contact lens care solutionContact lens wear
Abbott Medical Optics, Inc160 enrolled1 locationACTRN12609000640202
Completed
Phase 3Phase 4
Crystalloid versus Hydroxy-Ethyl Starch Trial - A multi-centre randomized controlled trial of fluid resuscitation with starch (6% hydroxyl starch 130/0/4) compared to saline (0.9%) sodium chloride in intensive care patients on mortality.
Fluid resuscitation in intensive care patients
The George Institute for Global Health7,000 enrolled2 locationsACTRN12609000245291
Terminated
Phase 3
Dexmedetomidine and Haloperidol for the management of emergence delirium in intensive care
Delirium in mechanically ventilated intensive care patients
Prince of Wales Hospital60 enrolled1 locationACTRN12606000085572
Completed
Phase 3
A randomised controlled trial of a question prompt list for palliative care patients and their caregivers
Patients, and their cargeivers, with advanced progressive life limiting illnesses being referred for palliative care
Medical Psychology Research Unit, University of Sydney160 enrolled1 locationACTRN12605000301662
Active
Phase 3
Randomised controlled trial of maintenance fluids in paediatric intensive care.
Children admitted to paediatric intensive care (PICU)
Women's and Children's Hospital Adelaide. Not sponsored financially.48 enrolled1 locationACTRN12605000061639