Chordoma Clinical Trials

11 recruiting

Chordoma Trials at a Glance

14 actively recruiting trials for chordoma are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Nice, Baltimore, and Barcelona. Lead sponsors running chordoma studies include Centre Antoine Lacassagne, Hospices Civils de Lyon, and CNAO National Center of Oncological Hadrontherapy.

Browse chordoma trials by phase

Treatments under study

About Chordoma Clinical Trials

Looking for clinical trials for Chordoma? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chordoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chordoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting

Children and Adults With Chordoma

Chordoma
National Cancer Institute (NCI)300 enrolled1 locationNCT03910465
Recruiting

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone

ChondrosarcomaBone SarcomaChordoma+2 more
Mayo Clinic72 enrolled3 locationsNCT05033288
Recruiting
Phase 1Phase 2

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

OsteosarcomaEwing SarcomaNeuroblastoma+10 more
University of Florida27 enrolled1 locationNCT06625190
Recruiting
Not Applicable

Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base

ChondrosarcomaChordoma
Quironsalud20 enrolled1 locationNCT05861245
Recruiting
Phase 1Phase 2

A Study of ERAS-601 in People With Chordoma

Chordoma
Memorial Sloan Kettering Cancer Center46 enrolled7 locationsNCT06957327
Recruiting
Not Applicable

Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease

Chordoma
Italian Sarcoma Group100 enrolled28 locationsNCT02986516
Recruiting

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

Chordoma of SpineChordoma of Skull BaseChordoma of Sacrum
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins40 enrolled2 locationsNCT06463262
Recruiting

Long-Term Longitudinal QoL in Patients Undergoing EEA

ChondrosarcomaMeningiomaPituitary Tumor+5 more
Ohio State University400 enrolled1 locationNCT04087902
Recruiting
Phase 2

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Chordoma

Chordoma
Sichuan Baili Pharmaceutical Co., Ltd.40 enrolled1 locationNCT06787664
Recruiting
Phase 2

Pembrolizumab and Pemetrexed for Progressive Chordoma

ChordomaChordomas
Saint John's Cancer Institute21 enrolled1 locationNCT06794645
Recruiting
Not Applicable

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

OsteosarcomaEwing SarcomaChondrosarcoma+1 more
Centre Antoine Lacassagne106 enrolled1 locationNCT06029218
Recruiting

Multi-parametric Imaging in Personalized Radiotherapy

Skull Base Chordoma
CNAO National Center of Oncological Hadrontherapy35 enrolled1 locationNCT05888064
Recruiting

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas

ChondrosarcomaMagnetic Resonance ImagingChordoma+1 more
Leiden University Medical Center40 enrolled2 locationsNCT04832620
Recruiting
Not Applicable

Randomized Carbon Ions vs Standard Radiotherapy for Radioresistant Tumors

Malignant Tumors as Chordoma, Adenoid Cystic Carcinoma and Sarcoma
Hospices Civils de Lyon250 enrolled21 locationsNCT02838602